Inferring population structure in biobank-scale genomic data.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2022.02.015
Abstract: Inferring the structure of human populations from genetic variation data is a key task in population and medical genomic studies. Although a number of methods for population structure inference have been proposed, current methods are… read more here.
Keywords: population structure; scale genomic; structure; inferring population ... See more keywords
Large-scale genomic analyses of in vitro yeast-mycelium dimorphism in human, insect and plant pathogenic fungi: From ESTs to RNAseq experiments
Sign Up to like & getrecommendations! Published in 2017 at "Fungal Biology Reviews"
DOI: 10.1016/j.fbr.2017.04.001
Abstract: Abstract Yeast-mycelium fungal dimorphism is a complex trait studied for many years, particularly in pathogenic fungi for which the morphological switch is often associated with virulence. It is a characteristic shared by many species from… read more here.
Keywords: large scale; dimorphism; pathogenic fungi; scale genomic ... See more keywords
SLEMM: million-scale genomic predictions with window-based SNP weighting
Sign Up to like & getrecommendations! Published in 2023 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btad127
Abstract: Abstract Motivation The amount of genomic data is increasing exponentially. Using many genotyped and phenotyped individuals for genomic prediction is appealing yet challenging. Results We present SLEMM (short for Stochastic-Lanczos-Expedited Mixed Models), a new software… read more here.
Keywords: snp weighting; slemm million; million scale; scale genomic ... See more keywords
Integration of Large-Scale Genomic Data Sources With Evolutionary History Reveals Novel Genetic Loci for Congenital Heart Disease
Sign Up to like & getrecommendations! Published in 2019 at "Circulation. Genomic and Precision Medicine"
DOI: 10.1161/circgen.119.002694
Abstract: Supplemental Digital Content is available in the text. read more here.
Keywords: scale genomic; genomic data; large scale; sources evolutionary ... See more keywords
The theory on and software simulating large-scale genomic data for genotype-by-environment interactions
Sign Up to like & getrecommendations! Published in 2021 at "BMC Genomics"
DOI: 10.1186/s12864-021-08191-z
Abstract: Background With the emphasis on analysing genotype-by-environment interactions within the framework of genomic selection and genome-wide association analysis, there is an increasing demand for reliable tools that can be used to simulate large-scale genomic data… read more here.
Keywords: genomic data; scale genomic; large scale; genotype environment ... See more keywords
Large scale genomic analysis of 3067 SARS-CoV-2 genomes reveals a clonal geo-distribution and a rich genetic variations of hotspots mutations
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0240345
Abstract: In late December 2019, an emerging viral infection COVID-19 was identified in Wuhan, China, and became a global pandemic. Characterization of the genetic variants of SARS-CoV-2 is crucial in following and evaluating it spread across… read more here.
Keywords: large scale; analysis; cov genomes; scale genomic ... See more keywords