New approach to optimizing risk management of the sticking problem using scale-independent critical material attributes and the quantitative process parameter.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119032
Abstract: In pharmaceutical manufacturing of solid formulations, blending with a lubricant is a key process in preventing sticking during compression. Sticking not only results in tablets with a disfigured appearance but also brings about the interruption… read more here.
Keywords: critical material; process; independent critical; scale independent ... See more keywords
Scale-independent microfluidic production of cationic liposomal adjuvants and development of enhanced lymphatic targeting strategies.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.9b00730
Abstract: Cationic liposomes prepared from dimethyldioctadecylammonium bromide (DDAB) and trehalose 6,6'-dibehenate (TDB) are strong liposomal adjuvants. As with many liposome formulations, within the laboratory DDAB:TDB is commonly prepared by the thin film method which is difficult… read more here.
Keywords: cationic liposomal; liposomal adjuvants; microfluidic production; lymphatic targeting ... See more keywords