Manufacturing readiness assessment for evaluation of the microneedle array patch industry: an exploration of barriers to full-scale manufacturing.
Sign Up to like & getrecommendations! Published in 2021 at "Drug delivery and translational research"
DOI: 10.1007/s13346-021-01076-4
Abstract: Microneedle array patch (MAP) technology is a promising new delivery technology for vaccines and pharmaceuticals, yet due to several differing and novel production methods, barriers to full-scale manufacturing exist. PATH conducted a manufacturing readiness assessment… read more here.
Keywords: manufacturing readiness; scale manufacturing; manufacturing; map ... See more keywords
Large-scale manufacturing of ultra-strong, strain-responsive poly(lactic acid)-based nanocomposites reinforced with cellulose nanocrystals
Sign Up to like & getrecommendations! Published in 2020 at "Composites Science and Technology"
DOI: 10.1016/j.compscitech.2020.108144
Abstract: Abstract Developing materials from renewable resources to produce nanocomposites with satisfactory mechanical properties is a vital progress in today's society, and meanwhile, the widespread use of these nanocomposites needs to be enabled through large-scale manufacturing.… read more here.
Keywords: large scale; poly lactic; ultra strong; scale manufacturing ... See more keywords
Optimization of large-scale manufacturing of biopolymeric and lipid nanoparticles using microfluidic swirl mixers.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2022.121762
Abstract: Nanoparticles (NPs) have great potential as efficient drug delivery systems (DDSs) that have been widely used in cancer therapy and vaccines especially in the past decade. The rise in demand from the pharmaceutical industry drives… read more here.
Keywords: scale manufacturing; optimization large; lipid nanoparticles; large scale ... See more keywords
Prioritizing Digitalization Use Cases during Early Development Phases of Large Scale Manufacturing Systems
Sign Up to like & getrecommendations! Published in 2019 at "Procedia Manufacturing"
DOI: 10.1016/j.promfg.2018.12.007
Abstract: Abstract Manufacturing processes are becoming increasingly complex. In order to stay competitive, speeding up knowledge generation about the processes, products and their interdependencies is necessary. Digitalization and data analytics provide the required toolset to uncover… read more here.
Keywords: scale manufacturing; manufacturing; development phases; early development ... See more keywords
Process Development for Adoptive Cell Therapy in Academia: A Pipeline for Clinical-Scale Manufacturing of Multiple TCR-T Cell Products
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.896242
Abstract: Cellular immunotherapies based on T cell receptor (TCR) transfer are promising approaches for the treatment of cancer and chronic viral infections. The discovery of novel receptors is expanding considerably; however, the clinical development of TCR-T… read more here.
Keywords: tcr cell; scale manufacturing; cell; tcr ... See more keywords
Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9030092
Abstract: Allogeneic cell therapy products, such as therapeutic cells derived from pluripotent stem cells (PSCs), have amazing potential to treat a wide variety of diseases and vast numbers of patients globally. However, there are various challenges… read more here.
Keywords: scale manufacturing; cell; scale; pluripotent stem ... See more keywords