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   Articles with "scap" as a keyword



Erythropoietin (rhEPOa) promotes endothelial transdifferentiation of stem cells of the apical papilla (SCAP).

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recommendations! Published in 2018 at "Archives of oral biology"

DOI: 10.1016/j.archoralbio.2018.09.001

Abstract: OBJECTIVE Mesenchymal stem cells (MSCs) have attracted worldwide attention for their capacity to repair damaged tissue, immunosuppression, ability to differentiate into several cell types and their secretome. Earlier studies have demonstrated their angiogenic potential in… read more here.

Keywords: endothelial transdifferentiation; apical papilla; scap; stem cells ... See more keywords

Vitamin D Metabolite, 25-Hydroxyvitamin D, Regulates Lipid Metabolism by Inducing Degradation of SREBP/SCAP.

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recommendations! Published in 2017 at "Cell chemical biology"

DOI: 10.1016/j.chembiol.2016.12.017

Abstract: Sterol regulatory element-binding proteins (SREBPs) are transcription factors that control lipid homeostasis. SREBP activation is regulated by a negative feedback loop in which sterols bind to SREBP cleavage-activating protein (SCAP), an escort protein essential for… read more here.

Keywords: degradation; srebp; scap; srebp activation ... See more keywords

Effect of bFGF on the growth and matrix turnover of stem cells from human apical papilla: Role of MEK/ERK signaling.

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recommendations! Published in 2020 at "Journal of the Formosan Medical Association = Taiwan yi zhi"

DOI: 10.1016/j.jfma.2019.12.013

Abstract: BACKGROUND/PURPOSE Basic fibroblast growth factor (bFGF) exhibits multiple biological functions in various tissues. Stem cells from apical papilla (SCAP) can be isolated from human apical papilla tissues in developmental teeth of children. The purposes of… read more here.

Keywords: mek erk; apical papilla; bfgf; scap ... See more keywords

Evaluation of mesenchymal stem cell modulation of trigeminal neuronal responses to cold

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recommendations! Published in 2017 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2017.07.050

Abstract: Tissue engineering protocols, such as regenerative endodontic procedures (REPs), comprise biologically based procedures designed to restore normal physiologic function. For REPs, the goal is reconstitution of the pulp-dentin complex by delivering mesenchymal stem cells (MSCs),… read more here.

Keywords: neuronal responses; scap; stem; culture ... See more keywords

Dysfunction of cholesterol sensor SCAP promotes inflammation activation in THP‐1 macrophages

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recommendations! Published in 2018 at "Experimental Cell Research"

DOI: 10.1016/j.yexcr.2018.03.032

Abstract: ABSTRACT Crosstalk occurs between dyslipidemia and chronic inflammation, which are both precipitants of atherosclerosis. Sterol regulatory element binding proteins cleavage‐activating protein (SCAP) plays a key role in regulating cholesterol homeostasis. The present study investigated the… read more here.

Keywords: dysfunction; cholesterol; scap; expression ... See more keywords

Optimal approaches to preventing severe community-acquired pneumonia

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recommendations! Published in 2019 at "Expert Review of Respiratory Medicine"

DOI: 10.1080/17476348.2019.1656531

Abstract: ABSTRACT Introduction: Community-acquired pneumonia (CAP) has the highest rate of mortality of all infectious diseases, especially among the elderly. Severe CAP (sCAP) is defined as a CAP in which intensive care management is required and… read more here.

Keywords: optimal approaches; community acquired; scap; cap ... See more keywords

Electric field promoted odontogenic differentiation of stem cells from apical papilla by remodelling cytoskeleton

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recommendations! Published in 2025 at "International Endodontic Journal"

DOI: 10.1111/iej.14213

Abstract: Abstract Aim This study examined the impact of direct current electric fields (DCEFs) on the biological properties of stem cells derived from the apical papilla (SCAP) and further elucidated the underlying mechanisms involved in odontogenic… read more here.

Keywords: differentiation; scap; stem cells; odontogenic differentiation ... See more keywords

Mitochondrial Function Is Required to Preserve Viability of Stem Cells From the Apical Papilla Following Porphyromonas endodontalis Infection.

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recommendations! Published in 2025 at "International endodontic journal"

DOI: 10.1111/iej.70058

Abstract: AIMS To investigate the effects of Porphyromonas endodontalis on the viability of stem cells from the apical papilla (SCAP) and to explore the role of mitochondrial function in supporting SCAP survival. METHODOLOGY SCAP were isolated… read more here.

Keywords: scap; mitochondrial fission; endodontalis infection; infection ... See more keywords

Abstract 1457: SCAP/SREBP-1 regulates lipid metabolism reprogramming in cancer cell

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recommendations! Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-1457

Abstract: Warburg initial observation shows tumorigenesis is associated with an increased glucose consumption. Recently, accumulating evidence show that lipid metabolism is reprogrammed in cancers. Elevated lipogenesis which contributes to the development of malignant phenotypes is known… read more here.

Keywords: srebp; scap; cancer cell; cancer ... See more keywords

miR-486-5p predicted adverse outcomes of SCAP and regulated K. pneumonia infection via FOXO1

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recommendations! Published in 2024 at "BMC Immunology"

DOI: 10.1186/s12865-024-00624-0

Abstract: Purpose Severe community-acquired pneumonia (SCAP) is a common respiratory system disease with rapid development and high mortality. Exploring effective biomarkers for early detection and development prediction of SCAP is of urgent need. The function of… read more here.

Keywords: scap; pneumonia; 486 predicted; mir 486 ... See more keywords

Comparison of initial empirical antibiotic regimens in severe community-acquired pneumonia: a network meta-analysis

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recommendations! Published in 2025 at "BMC Pulmonary Medicine"

DOI: 10.1186/s12890-025-03695-w

Abstract: Severe community-acquired pneumonia (SCAP) remains a leading cause of morbidity and mortality worldwide. Identifying the optimal antibiotic regimen for treating SCAP is crucial for improving patient outcomes. We searched the PubMed, Embase, and Cochrane Central… read more here.

Keywords: scap; meta analysis; lactam antibiotics; network meta ... See more keywords