Exosomes derived from human hypertrophic scar fibroblasts induces smad and TAK1 signaling in normal dermal fibroblasts.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2022.109215
Abstract: Post-burn hypertrophic scars are characterized by excessive accumulation of extracellular matrix secreted by fibroblasts. Exosomes are membrane lipid extracellular vesicles that play a pivotal role in cellular communication. Previous studies revealed the role of stem… read more here.
Keywords: scar fibroblasts; htsfs derived; hypertrophic scar; exosomes derived ... See more keywords
Allicin inhibits proliferation and promotes apoptosis of human epidural scar fibroblasts.
Sign Up to like & getrecommendations! Published in 2020 at "World neurosurgery"
DOI: 10.1016/j.wneu.2020.01.031
Abstract: BACKGROUND Allicin can suppress liver and cardiac fibrosis, thus we hypothesize that it may prevent scar tissue from extensive epidural fibrosis after laminectomy. METHODS Human epidural scar fibroblasts were isolated from surgical specimen, and treated… read more here.
Keywords: phase; epidural scar; proliferation; human epidural ... See more keywords
tRNA-derived small RNAs: A novel class of small RNAs in human hypertrophic scar fibroblasts
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2019.4411
Abstract: tRNA-derived small RNAs (tsRNAs) have been shown to play regulatory roles in many physiological and pathological processes. However, their roles in hypertrophic scars remain unclear. The present study investigated differentially expressed tsRNAs in human hypertrophic… read more here.
Keywords: hypertrophic scar; human hypertrophic; small rnas; scar fibroblasts ... See more keywords