Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.09.008
Abstract: Spiny mice (Acomys cahirinus) are terrestrial mammals that evolved unique scar-free regenerative wound-healing properties. Myofibroblasts (MFs) are the major scar-forming cell type in skin. We found that following traumatic injury to ear pinnae, MFs appeared… read more here.
Keywords: wound healing; scar free; fate; spiny mice ... See more keywords
Setting up the dermis for scar-free healing
Sign Up to like & getrecommendations! Published in 2018 at "Nature Cell Biology"
DOI: 10.1038/s41556-018-0080-9
Abstract: During mouse back skin development, subsets of fibroblastic lineages transition from anti-fibrotic Engrailed-1 (En1) negative to pro-fibrotic En1-positive cells. Injuries of adult skin heal with scarring, whereas En1-deficient embryonic fibroblasts have the potential to promote… read more here.
Keywords: free healing; setting dermis; biology; dermis scar ... See more keywords
The potential of functionalized dressing releasing flavonoids facilitates scar-free healing
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.978120
Abstract: Scars are pathological marks left after an injury heals that inflict physical and psychological harm, especially the great threat to development and aesthetics posed by oral and maxillofacial scars. The differential expression of genes such… read more here.
Keywords: flavonoids facilitates; dressing releasing; functionalized dressing; releasing flavonoids ... See more keywords
Optimization of Surface-Engineered Micropatterns on Bacterial Cellulose for Guided Scar-Free Skin Wound Healing
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13050793
Abstract: Bacterial cellulose (BC) has been widely used in tissue engineering due to its unique spatial structure and suitable biological properties. In this study, a small biologically active Arginine-Glycine-Aspartic acid-Serine (RGDS) tetrapeptide was incorporated on the… read more here.
Keywords: bacterial cellulose; wound healing; surface; scar free ... See more keywords
Scar-Free Healing: Current Concepts and Future Perspectives
Sign Up to like & getrecommendations! Published in 2020 at "Nanomaterials"
DOI: 10.3390/nano10112179
Abstract: Every year, millions of people develop scars due to skin injuries after trauma, surgery, or skin burns. From the beginning of wound healing development, scar hyperplasia, and prolonged healing time in wound healing have been… read more here.
Keywords: free healing; wound healing; current concepts; healing current ... See more keywords