Type V collagen limits cardiac scar size
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DOI: 10.1038/s41569-020-0423-7
Abstract: Type V collagen, a minor constituent of the myocardial scar that forms after ischaemic injury, is an important regulator of scar size via a previously unrecognized role in limiting integrin-dependent fibrosis. read more here.
Keywords: type collagen; scar; scar size;
Connexin 43 Deficiency Is Associated with Reduced Myocardial Scar Size and Attenuated TGFβ1 Signaling after Transient Coronary Occlusion in Conditional Knock-Out Mice
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DOI: 10.3390/biom10040651
Abstract: Previous studies demonstrated a reduction in myocardial scar size in heterozygous Cx43+/- mice subjected to permanent coronary occlusion. However, patients presenting with ST segment elevation myocardial infarction often undergo rapid coronary revascularization leading to prompt… read more here.
Keywords: transient coronary; scar size; mice; coronary occlusion ... See more keywords