Simultaneous quantification of polysorbate 20 and poloxamer 188 in biopharmaceutical formulations using evaporative light scattering detection.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113640
Abstract: Polysorbates and Poloxamer 188 constitute the most common surfactants used in biopharmaceutical formulations owing to their excellent protein-stabilizing properties and good safety profiles. In recent years, however, a vast number of reports concerning potential risk… read more here.
Keywords: scattering detection; biopharmaceutical formulations; polysorbate poloxamer; evaporative light ... See more keywords
Light-scattering detection within the difficult size range of protein particle measurement using flow cytometry.
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DOI: 10.1039/c8nr05214j
Abstract: The phenomenon of protein aggregation is a prominent challenge that impacts biopharmaceutical development at every stage. It may have a number of deleterious effects on protein drugs, including the loss of efficacy, induction of immunogenicity,… read more here.
Keywords: protein; scattering detection; fcm system; range ... See more keywords
Raman scattering detection of high explosives on human hair
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DOI: 10.1117/1.oe.59.10.107103
Abstract: Abstract. High explosives (HE) represent a high risk to the safety and health of the general population. Therefore, there is an ongoing demand for methods of analysis with limits of detection at trace levels for… read more here.
Keywords: high explosives; scattering detection; raman scattering; human hair ... See more keywords