RA3 is a reference-guided approach for epigenetic characterization of single cells
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-22495-4
Abstract: The recent advancements in single-cell technologies, including single-cell chromatin accessibility sequencing (scCAS), have enabled profiling the epigenetic landscapes for thousands of individual cells. However, the characteristics of scCAS data, including high dimensionality, high degree of… read more here.
Keywords: ra3 reference; sccas data; reference; reference guided ... See more keywords
RefTM: reference-guided topic modeling of single-cell chromatin accessibility data
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac540
Abstract: Single-cell analysis is a valuable approach for dissecting the cellular heterogeneity, and single-cell chromatin accessibility sequencing (scCAS) can profile the epigenetic landscapes for thousands of individual cells. It is challenging to analyze scCAS data, because… read more here.
Keywords: sccas data; cell; single cell; chromatin accessibility ... See more keywords