Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Science"
DOI: 10.1126/science.aao5774
Abstract: Microbial modulation of diabetes Short-chain fatty acids (SCFAs) are produced by various human gut microbes. SCFAs act as an energy source to the colonic epithelium and are also sensed by host signaling pathways that modulate… read more here.
Keywords: gut; scfa; type diabetes; type ... See more keywords
Fecal SCFAs and SCFA-producing bacteria in gut microbiome of human NAFLD as a putative link to systemic T-cell activation and advanced disease
Sign Up to like & getrecommendations! Published in 2018 at "United European Gastroenterology Journal"
DOI: 10.1177/2050640618804444
Abstract: Background Intestinal microbiota and their metabolites (e.g. short-chain fatty acids (SCFAs)) may influence nonalcoholic fatty liver disease (NAFLD). Objective The objective of this article is to analyze gut bacterial diversity together with fecal SCFA concentrations… read more here.
Keywords: human nafld; scfas; producing bacteria; scfa ... See more keywords
Association between Fecal Short-Chain Fatty Acid Levels, Diet, and Body Mass Index in Patients with Inflammatory Bowel Disease
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DOI: 10.3390/biology11010108
Abstract: Simple Summary Inflammatory bowel disease (IBD) is a chronic disorder of the gastrointestinal tract associated with gut inflammation and a disturbance in the amount of bacteria living in the human intestines. As a result, there… read more here.
Keywords: chain fatty; scfa; inflammatory bowel; scfa levels ... See more keywords
Dietary Fiber Treatment Corrects the Composition of Gut Microbiota, Promotes SCFA Production, and Suppresses Colon Carcinogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Genes"
DOI: 10.3390/genes9020102
Abstract: Epidemiological studies propose a protective role for dietary fiber in colon cancer (CRC). One possible mechanism of fiber is its fermentation property in the gut and ability to change microbiota composition and function. Here, we… read more here.
Keywords: microbiota; scfa; fiber; polyposis ... See more keywords
Enalapril Diminishes the Diabetes-Induced Changes in Intestinal Morphology, Intestinal RAS and Blood SCFA Concentration in Rats
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23116060
Abstract: Evidence suggests that microbiota-derived metabolites, including short-chain fatty acids (SCFAs) and trimethylamine-oxide (TMAO), affect the course of diabetic multiorgan pathology. We hypothesized that diabetes activates the intestinal renin–angiotensin system (RAS), contributing to gut pathology. Twelve-week-old… read more here.
Keywords: diabetic rats; scfa; morphology; expression ... See more keywords
The Microalgae Phaeodactylum tricornutum Is Well Suited as a Food with Positive Effects on the Intestinal Microbiota and the Generation of SCFA: Results from a Pre-Clinical Study
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14122504
Abstract: Microalgae such as Phaeodactylum tricornutum (PT) are a sustainable source of nutrients, especially eicosapentaenoic acid (EPA), fucoxanthin (Fx), and chrysolaminarin (Chrl), the concentrations of which can vary depending on the culture conditions. We generated three… read more here.
Keywords: clinical study; scfa; phaeodactylum tricornutum; microalgae phaeodactylum ... See more keywords
Short-Chain Fatty Acids Modulate Permeability, Motility and Gene Expression in the Porcine Fetal Jejunum Ex Vivo
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DOI: 10.3390/nu14122524
Abstract: Postnatally, short-chain fatty acids (SCFA) are important energetic and signaling agents, being involved in host nutrition, gut imprinting and immune and barrier function. Whether SCFA exert similar effects during the late fetal phase has been… read more here.
Keywords: fetal jejunum; scfa; expression; permeability ... See more keywords
Commensal microbe-derived SCFA alleviates atrial fibrillation via GPR43/NLRP3 signaling
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DOI: 10.7150/ijbs.70644
Abstract: Rationale: Dysbiotic gut microbiota (GM) and NLRP3 inflammasome are proarrhythmic factors in atrial fibrillation (AF). Herein, whether short-chain fatty acid (SCFA) produced from GM fermentation of dietary fiber serving as invisible mediators is yet unclear.… read more here.
Keywords: gpr43; dietary fiber; nlrp3 signaling; scfa ... See more keywords