Effects of divalent cations on Schaffer collateral axon function.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental brain research"
DOI: 10.1007/s00221-020-06026-z
Abstract: Previously, we reported that distal Schaffer collaterals undergo biphasic changes in excitability during high-frequency stimulation (HFS), with an early hyper-excitability period followed by an excitability depression period. The extracellular divalent cations calcium and magnesium can… read more here.
Keywords: schaffer collateral; effects divalent; divalent cations; magnesium ... See more keywords
Aß Facilitates LTD at Schaffer Collateral Synapses Preferentially in the Left Hippocampus.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.01.085
Abstract: Promotion of long-term depression (LTD) mechanisms by synaptotoxic soluble oligomers of amyloid-β (Aß) has been proposed to underlie synaptic dysfunction in Alzheimer's disease (AD). Previously, LTD was induced by relatively non-specific electrical stimulation. Exploiting optogenetics,… read more here.
Keywords: schaffer collateral; hippocampus; left hippocampus; ltd schaffer ... See more keywords
Neuregulin and Dopamine D4 Receptors Contribute Independently to Depotentiation of Schaffer Collateral LTP by Temperoammonic Path Stimulation
Sign Up to like & getrecommendations! Published in 2017 at "eNeuro"
DOI: 10.1523/eneuro.0176-17.2017
Abstract: Abstract Prior studies have found that dopamine (DA), acting at D4 receptors, and neuregulin (NRG), likely acting at ErbB4 receptors, are involved in a form of depotentiation of long-term potentiation (LTP) at Schaffer collateral (SC)… read more here.
Keywords: schaffer collateral; ltp; stimulation; depotentiation ... See more keywords