Metabolic mapping of Schisandra chinensis lignans and their metabolites in rats using a metabolomic approach based on HPLC with quadrupole time-of-flight MS/MS spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of separation science"
DOI: 10.1002/jssc.201900860
Abstract: Schisandra chinensis lignans are the main active components of traditional Chinese medicine Schisandra chinensis in East Asia. At present, there are more and more medicines and health foods in which the total Schisandra chinensis lignans… read more here.
Keywords: based hplc; chinensis; time; chinensis lignans ... See more keywords
Mass spectrometry-based urinary metabolomics for exploring the treatment effects of Radix ginseng-Schisandra chinensis herb pair on Alzheimer's disease in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of separation science"
DOI: 10.1002/jssc.202100061
Abstract: Herb pairs are the unique combinations of two relatively fixed herbs, intrinsically convey the basic idea of traditional Chinese medicine prescriptions. The compatibility of Radix ginseng and Schisandra chinensis has been used in traditional Chinese… read more here.
Keywords: ginseng schisandra; herb pair; radix ginseng; schisandra chinensis ... See more keywords
Pancreatic lipase and alpha-glucosidase inhibitors screening from Schisandra chinensis based on spectrum-effect relationship and ultra- high-performance liquid chromatography-tandem mass spectrometry.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200541
Abstract: As a traditional Chinese medicine, Schisandra chinensis has potential weight-loss effect by delaying carbohydrate absorption and improving lipid metabolic disorders. However, its active components are still unclear and require in-depth research. In this study, the… read more here.
Keywords: performance liquid; alpha glucosidase; schisandra chinensis; liquid chromatography ... See more keywords
Anti-melanogenic effect of gomisin N from Schisandra chinensis (Turcz.) Baillon (Schisandraceae) in melanoma cells
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Pharmacal Research"
DOI: 10.1007/s12272-017-0903-4
Abstract: Overproduction and accumulation of melanin in the skin can lead to pigmentation disorders, such as freckles and melasma. Many researchers are studying the regulation of melanogenesis in the skin with the aim of developing whitening… read more here.
Keywords: gomisin; melanoma cells; chinensis turcz; turcz baillon ... See more keywords
Inhibition of human CYP3A4 and CYP3A5 enzymes by gomisin C and gomisin G, two lignan analogs derived from Schisandra chinensis.
Sign Up to like & getrecommendations! Published in 2017 at "Fitoterapia"
DOI: 10.1016/j.fitote.2017.03.010
Abstract: Gomisin C (GC) and gomisin G (GG) are two lignan analogs isolated from the Traditional Chinese Medicine Schisandra chinensis which possesses multiple pharmacological activities. However, the potential herb-drug interactions (HDI) between these lignans and other… read more here.
Keywords: gomisin; cyp3a4 cyp3a5; cyp3a5; cyp3a4 ... See more keywords
Studies on non-medicinal parts of plant materials: Triterpenes from the roots of Schisandra chinensis.
Sign Up to like & getrecommendations! Published in 2021 at "Fitoterapia"
DOI: 10.1016/j.fitote.2021.104939
Abstract: Phytochemical study on a non-medicinal part of a plant materials for herbal medicines, the roots of Schisandra chinensis, was conducted to isolate five new triterpenes, schinensins A-D (1-4) and 3-O-methylchangnanic acid (5), together with 21… read more here.
Keywords: non medicinal; plant materials; schisandra chinensis; roots schisandra ... See more keywords
Effects of Schisandra chinensis polysaccharides on rats with antibiotic-associated diarrhea.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.11.250
Abstract: Schisandra chinensis (S. chinensis), a traditional Chinese medicine (TCM), is comprised of polysaccharides as its main active component. In this study, water-soluble polysaccharides from S. chinensis (WSP) were extracted, and their effects on rats with… read more here.
Keywords: chinensis; antibiotic associated; rats antibiotic; schisandra chinensis ... See more keywords
Purification, structural characterization, and cognitive improvement activity of a polysaccharides from Schisandra chinensis.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.06.275
Abstract: The present study aimed to evaluate structural characteristics of a polysaccharides, SCP2-1, isolated from Schisandra chinensis (Turcz.) Baill (S. chinensis) and to assess its improvement on cognitive dysfunction caused by excessive neuroinflammation. Structural characterization indicated… read more here.
Keywords: improvement; linked galp; chinensis; structural characterization ... See more keywords
Lignans from the fruits of Schisandra chinensis (Turcz.) Baill inhibit proprotein convertase subtilisin/kexin type 9 expression.
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DOI: 10.1016/j.phytochem.2017.01.010
Abstract: Bioactivity-guided fractionation of the fruits of Schisandra chinensis, using the proprotein convertase subtilisin-kexin type 9 (PCSK9) mRNA expression screening assay, led to isolation of two previously unknown lignans, 14-tigloylschinlignan D and rel-(7R, 8R, 7'R, 8'R)-manglisin… read more here.
Keywords: proprotein convertase; subtilisin kexin; expression; convertase subtilisin ... See more keywords
Candidate genes involved in the biosynthesis of lignan in Schisandra chinensis fruit based on transcriptome and metabolomes analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(20)60007-3
Abstract: Schisandra chinensis Turcz. (Baill.) is a plant species with fruits that have been well known in Far Eastern medicine for a long time. It has traditionally been used as a stimulating and fortifying agent in… read more here.
Keywords: genes involved; chinensis; involved lignan; lignan biosynthesis ... See more keywords
Schisandrin C isolated from Schisandra chinensis fruits inhibits lipid accumulation by regulating adipogenesis and lipolysis through AMPK signaling in 3T3-L1 adipocytes.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.14454
Abstract: In this study, lignans of Schisandra chinensis fruits (SCF) were profiled using HPLC-MS/MS, and the inhibitory effects of nine of these lignans were evaluated on triglyceride (TG) accumulation. We then examined the effects and molecular… read more here.
Keywords: adipogenesis; schisandra chinensis; lipolysis; chinensis fruits ... See more keywords