Improving docosahexaenoic acid production by Schizochytrium sp. using a newly designed high‐oxygen‐supply bioreactor
Sign Up to like & getrecommendations! Published in 2017 at "Aiche Journal"
DOI: 10.1002/aic.15783
Abstract: A sufficiently high oxygen supply is crucial for high-cell-density cultivation of aerobic microorganisms, including Schizochytrium sp. We, therefore, designed a novel bioreactor enabling high-level oxygen supply, and its relevant process parameters and fermentation-stage characteristics were… read more here.
Keywords: bioreactor; dha; oxygen supply; schizochytrium ... See more keywords
Assessing the potential of Schizochytrium sp. HX-308 for microbial lipids production from corn stover hydrolysate.
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology journal"
DOI: 10.1002/biot.202100470
Abstract: Schizochytrium sp. has received increasing attention as promising commercial resource for the sustainable production of lipids, due to their fast growth rate and high lipid content. However, the price of glucose represents a significant proportion… read more here.
Keywords: schizochytrium 308; corn stover; stover hydrolysate; schizochytrium ... See more keywords
Improvement of docosahexaenoic acid fermentation from Schizochytrium sp. AB‐610 by staged pH control based on cell morphological changes
Sign Up to like & getrecommendations! Published in 2017 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.201600249
Abstract: Schizochytrium sp. AB‐610 accumulates relatively higher amount of DHA‐rich lipid in the cells, and it was found that DHA yield was closely related to the cell morphology and pH value during fermentation period. DHA production… read more here.
Keywords: fermentation; schizochytrium 610; dha; schizochytrium ... See more keywords
Extracted microbial oil from a novel Schizochytrium sp. (T18) as a sustainable high DHA source for Atlantic salmon feed: Impacts on growth and tissue lipids
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DOI: 10.1016/j.aquaculture.2020.736249
Abstract: Abstract The use of microbial oil, high in docosahexaenoic acid (DHA), was investigated as a lipid source in diets for farmed Atlantic salmon. Schizochytrium sp. oil is produced from heterotrophic fermentation and it can be… read more here.
Keywords: schizochytrium t18; microbial oil; dha; schizochytrium ... See more keywords
High-value utilization of the waste hydrolysate of Dioscorea zingiberensis for docosahexaenoic acid production in Schizochytrium sp.
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DOI: 10.1016/j.biortech.2021.125305
Abstract: The starch saccharification liquid of Dioscorea zingiberensis tubers (SSLD) is a glucose-rich agro-industrial waste. Herein, SSLD was used as a novel potential carbon source for the biosynthesis of docosahexaenoic acid (DHA) in Schizochytrium sp. to… read more here.
Keywords: docosahexaenoic acid; high value; dioscorea zingiberensis; waste ... See more keywords
Enhancement of lipid accumulation and docosahexaenoic acid synthesis in Schizochytrium sp. H016 by exogenous supplementation of sesamol.
Sign Up to like & getrecommendations! Published in 2021 at "Bioresource technology"
DOI: 10.1016/j.biortech.2021.126527
Abstract: Schizochytrium sp. is one of the most promising marine oleaginous microorganisms for industrial production of docosahexaenoic acid (DHA). In this study, the exogenous supplementation of 1 mM sesamol to the fermentation medium effectively prevented the… read more here.
Keywords: exogenous supplementation; schizochytrium; sesamol; docosahexaenoic acid ... See more keywords
Production of polyunsaturated fatty acids by Schizochytrium (Aurantiochytrium) spp.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology advances"
DOI: 10.1016/j.biotechadv.2021.107897
Abstract: Diverse health benefits are associated with dietary consumption of omega-3 long-chain polyunsaturated fatty acids (ω-3 LC-PUFA), particularly docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). Traditionally, these fatty acids have been obtained from fish oil, but… read more here.
Keywords: aurantiochytrium spp; schizochytrium; polyunsaturated fatty; production ... See more keywords
Zinc Finger Protein LipR Represses Docosahexaenoic Acid and Lipid Biosynthesis in Schizochytrium sp.
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DOI: 10.1128/aem.02063-21
Abstract: Regulatory mechanisms for DHA and saturated fatty acid biosynthesis in the heterotrophic marine microalgae Schizochytrium sp. are unclear. We demonstrate here that deletion of the gene (lipR) encoding the C2H2 zinc finger protein LipR promotes… read more here.
Keywords: schizochytrium; biosynthesis; finger protein; protein lipr ... See more keywords
Transcriptome Analysis Reveals an Eicosapentaenoic Acid Accumulation Mechanism in a Schizochytrium sp. Mutant
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DOI: 10.1128/spectrum.00130-23
Abstract: Schizochytrium, a marine eukaryotic microorganism, has emerged as a candidate for the commercial production of PUFAs. EPA is an omega-3 PUFA with preventive and therapeutic effects against cardiovascular diseases, schizophrenia, and other disorders. ABSTRACT Eicosapentaenoic… read more here.
Keywords: schizochytrium; epa; schizochytrium spp; production ... See more keywords
Overproduction of docosahexaenoic acid in Schizochytrium sp. through genetic engineering of oxidative stress defense pathways
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DOI: 10.1186/s13068-021-01918-w
Abstract: Background Oxidation and peroxidation of lipids in microorganisms result in increased levels of intracellular reactive oxygen species (ROS) and reactive aldehydes, and consequent reduction of cell growth and lipid accumulation. Results To reduce oxygen-mediated cell… read more here.
Keywords: oxidative stress; stress defense; schizochytrium; cell ... See more keywords
An emerging simple and effective approach to increase the productivity of thraustochytrids microbial lipids by regulating glycolysis process and triacylglycerols’ decomposition
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DOI: 10.1186/s13068-021-02097-4
Abstract: Background The oleaginous microorganism Schizochytrium sp. is widely used in scientific research and commercial lipid production processes. However, low glucose-to-lipid conversion rate (GLCR) and low lipid productivity of Schizochytrium sp. restrict the feasibility of its… read more here.
Keywords: productivity; schizochytrium; microbial lipids; effective approach ... See more keywords