The phenolic interactome and gut microbiota: opportunities and challenges in developing applications for schizophrenia and autism
Sign Up to like & getrecommendations! Published in 2019 at "Psychopharmacology"
DOI: 10.1007/s00213-019-05267-3
Abstract: Schizophrenia and autism spectrum disorder have long been associated with elevated levels of various small phenolic molecules (SPMs). In turn, the gut microbiota (GMB) has been implicated in the kinetics of many of these analytes. Unfortunately,… read more here.
Keywords: schizophrenia autism; autism; phenolic interactome; gut microbiota ... See more keywords
Genetic and environmental factors of schizophrenia and autism spectrum disorder: insights from twin studies
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-020-02188-w
Abstract: Twin studies of psychiatric disorders such as schizophrenia and autism spectrum disorder have employed epidemiological approaches that determine heritability by comparing the concordance rate between monozygotic twins (MZs) and dizygotic twins. The basis for these… read more here.
Keywords: schizophrenia autism; environmental factors; psychiatric disorders; spectrum disorder ... See more keywords
Altered empathy-related resting-state functional connectivity in adolescents with early-onset schizophrenia and autism spectrum disorders.
Sign Up to like & getrecommendations! Published in 2020 at "Asian journal of psychiatry"
DOI: 10.1016/j.ajp.2020.102167
Abstract: Empathy refers to the ability to understand other people's feelings and reacting emotionally to others. Impaired empathy has been reported in both individuals with schizophrenia and autism spectrum disorders (ASD). Despite overlaps, few studies have… read more here.
Keywords: schizophrenia autism; connectivity; resting state; state functional ... See more keywords
Mini-review: Brain energy metabolism and its role in animal models of depression, bipolar disorder, schizophrenia and autism
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2021.136003
Abstract: Mitochondria are cellular organelles essential for energy metabolism and antioxidant defense. Mitochondrial impairment is implicated in many psychiatric disorders, including depression, bipolar disorder, schizophrenia, and autism. To characterize and eventually find effective treatments of bioenergetic… read more here.
Keywords: depression bipolar; schizophrenia autism; bipolar disorder; disorder schizophrenia ... See more keywords
Overlaps in brain dynamic functional connectivity between schizophrenia and autism spectrum disorder
Sign Up to like & getrecommendations! Published in 2019 at "Scientific African"
DOI: 10.1016/j.sciaf.2018.e00019
Abstract: Abstract Schizophrenia and autism share some genotipic and phenotypic aspects as connectome miswiring and common cognitive deficits. Currently, there are no medical tests available for either disorders, and diagnostics for both of them include direct… read more here.
Keywords: schizophrenia autism; autism; dynamic functional; functional connectivity ... See more keywords
Insulin-growth-factor-1 (IGF-1): just a few steps behind the evidence in treating schizophrenia and/or autism
Sign Up to like & getrecommendations! Published in 2018 at "CNS Spectrums"
DOI: 10.1017/s1092852918001256
Abstract: I have read with interest the article recently published in CNS Spectrums by Tayeb et al, in which they have given an overview of the available literature on the schizophrenia metabolome with the aim of… read more here.
Keywords: schizophrenia autism; schizophrenia; factor igf; treatment ... See more keywords
Machine-learning classification using neuroimaging data in schizophrenia, autism, ultra-high risk and first-episode psychosis
Sign Up to like & getrecommendations! Published in 2020 at "Translational Psychiatry"
DOI: 10.1038/s41398-020-00965-5
Abstract: Neuropsychiatric disorders are diagnosed based on behavioral criteria, which makes the diagnosis challenging. Objective biomarkers such as neuroimaging are needed, and when coupled with machine learning, can assist the diagnostic decision and increase its reliability.… read more here.
Keywords: machine; schizophrenia autism; schizophrenia; machine learning ... See more keywords
Damaging coding variants within kainate receptor channel genes are enriched in individuals with schizophrenia, autism and intellectual disabilities
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-55635-4
Abstract: Schizophrenia (Scz), autism spectrum disorder (ASD) and intellectual disability are common complex neurodevelopmental disorders. Kainate receptors (KARs) are ionotropic glutamate ion channels involved in synaptic plasticity which are modulated by auxiliary NETO proteins. Using UK10K… read more here.
Keywords: schizophrenia autism; missense variants; intellectual disability; autism ... See more keywords
Vitamin-D Deficiency As a Potential Environmental Risk Factor in Multiple Sclerosis, Schizophrenia, and Autism
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2017.00047
Abstract: In this short review, we want to summarize the current findings on the role of vitamin-D in multiple sclerosis (MS), schizophrenia, and autism. Many studies have highlighted hypovitaminosis-D as a potential environmental risk factor for… read more here.
Keywords: schizophrenia autism; environmental risk; multiple sclerosis; factor ... See more keywords
Glutamatergic Dysfunction and Synaptic Ultrastructural Alterations in Schizophrenia and Autism Spectrum Disorder: Evidence from Human and Rodent Studies
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22010059
Abstract: The correlation between dysfunction in the glutamatergic system and neuropsychiatric disorders, including schizophrenia and autism spectrum disorder, is undisputed. Both disorders are associated with molecular and ultrastructural alterations that affect synaptic plasticity and thus the… read more here.
Keywords: schizophrenia autism; spectrum disorder; autism spectrum; ultrastructural alterations ... See more keywords