Neurocognitive Development in Children at Familial High Risk of Schizophrenia or Bipolar Disorder.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2022.0465
Abstract: Importance Neurocognitive impairments exist in children at familial high risk (FHR) of schizophrenia and bipolar disorder. Studies on preadolescent developmental courses of neurocognition are important to describe shared and distinct neurodevelopmental pathways in these groups.… read more here.
Keywords: fhr schizophrenia; bipolar disorder; children fhr; schizophrenia bipolar ... See more keywords
Comparison of social functioning in community‐living older individuals with schizophrenia and bipolar disorder: a catchment area‐based study
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.4490
Abstract: Preserved social functioning is of utmost importance for older individuals living in the community to maintain independency. However, in patients with schizophrenia or bipolar disorder, it remains unclear which factors influence social functioning in later… read more here.
Keywords: functioning; community; bipolar disorder; schizophrenia bipolar ... See more keywords
Schizophrenia, Bipolar Disorder, and Alzheimer’s Disease are not Causal Factors of Bone Mineral Density: A Mendelian Randomization Analysis
Sign Up to like & getrecommendations! Published in 2019 at "Calcified Tissue International"
DOI: 10.1007/s00223-019-00625-x
Abstract: Until recently, it remains unclear whether schizophrenia, bipolar disorder (BD), and Alzheimer’s disease (AD) is associated with bone mineral density (BMD). We aimed to investigate the causal effects of schizophrenia, BD and AD on BMD… read more here.
Keywords: schizophrenia; bmd; bmd bmd; causal ... See more keywords
Dissimilar social cognition signatures in remitted schizophrenia and bipolar disorder.
Sign Up to like & getrecommendations! Published in 2021 at "Asian journal of psychiatry"
DOI: 10.1016/j.ajp.2021.102593
Abstract: In the light of shared genetic underpinnings of schizophrenia and bipolar disorder, their comparative profile of social cognition (SC) performance - an intermittent phenotype and determinant of functional outcome - is poorly understood. Using data… read more here.
Keywords: social cognition; dissimilar social; bipolar disorder; schizophrenia bipolar ... See more keywords
Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.06.005
Abstract: BACKGROUND Several studies have described an association between childhood maltreatment and inflammatory markers in the psychotic disorders (schizophrenia [SZ] and bipolar disorder [BD]). Previous studies have been relatively small ( read more here.
Keywords: body mass; childhood; severity; schizophrenia bipolar ... See more keywords
HLA typing using genome wide data reveals susceptibility types for infections in a psychiatric disease enriched sample
Sign Up to like & getrecommendations! Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2018.03.001
Abstract: BACKGROUND The infections Toxoplasma gondii (T. gondii), cytomegalovirus, and Herpes Simplex Virus Type 1 (HSV1) are common persistent infections that have been associated with schizophrenia and bipolar disorder. The major histocompatibility complex (MHC, termed HLA… read more here.
Keywords: schizophrenia bipolar; genome wide; hla typing; hla ... See more keywords
Integrative Transcriptomics Reveals Sexually Dimorphic Control of the Cholinergic/Neurokine Interface in Schizophrenia and Bipolar Disorder
Sign Up to like & getrecommendations! Published in 2019 at "Cell Reports"
DOI: 10.1016/j.celrep.2019.09.017
Abstract: Summary RNA sequencing analyses are often limited to identifying lowest p value transcripts, which does not address polygenic phenomena. To overcome this limitation, we developed an integrative approach that combines large-scale transcriptomic meta-analysis of patient… read more here.
Keywords: schizophrenia bipolar; transcriptomics reveals; reveals sexually; bipolar disorder ... See more keywords
SU20 FUNCTIONAL LD CLUMP ENRICHMENT TEST (FLEET) DETECTS ENRICHMENT OF RISK LOCI FOR SCHIZOPHRENIA AND BIPOLAR DISORDER IN REGULATORY ELEMENTS AND PATHWAYS
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.209
Abstract: Background Genome-Wide Association Studies (GWASs) provide a wealth of information that can serve as a backbone for making biological inferences. There are over 160 loci reported with genome-wide significant association with Schizophrenia (SZ) and Bipolar… read more here.
Keywords: genome wide; risk; fleet; biology ... See more keywords
SU76 INCREASED FREQUENCY OF RARE GENETIC DISEASE VARIANTS IN LARGE SCHIZOPHRENIA, BIPOLAR, AND DEPRESSION POPULATIONS
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.265
Abstract: Background Genetic diseases are individually rare but collectively common. Many genetic conditions can mimic mental health disorders, with psychiatric symptoms that are difficult to treat with regular medications. Treatment of the underlying genetic disease can… read more here.
Keywords: disease; genetic disease; schizophrenia bipolar; genetic diseases ... See more keywords
M25 GENETICS OF COGNITIVE FUNCTION IN SCHIZOPHRENIA AND BIPOLAR DISORDER
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.332
Abstract: Background Cognitive impairment is a frequent and serious problem in patients with various forms of severe mental illnesses, including Schizophrenia (SZ) and Bipolar Disorder (BP). Cognitive performance in patients with bipolar disorder or schizophrenia has… read more here.
Keywords: schizophrenia; genetics; schizophrenia bipolar; performance ... See more keywords
M87 WHOLE GENOME SEQUENCING OF MULTIPLY-AFFECTED SCHIZOPHRENIA AND BIPOLAR DISORDER FAMILIES FROM THE AZORES AND MADEIRA
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.394
Abstract: Background Schizophrenia (SZ) and Bipolar Disorder (BP) are debilitating neuropsychiatric disorders, each affecting 0.5–1% of the world's population, and for which a shared polygenic liability has been demonstrated. Here, we consider recent progress in an… read more here.
Keywords: multiply affected; whole genome; azores madeira; bipolar disorder ... See more keywords