Memantine in neurological disorders - schizophrenia and depression.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular medicine"
DOI: 10.1007/s00109-020-01982-z
Abstract: Memantine is used in Alzheimer's disease treatment as a non-competitive modern-affinity strong voltage-dependent N-methyl-D-aspartate receptor antagonist. The fundamental role of these receptors is to bind glutamate: the main excitatory neurotransmitter in the brain, believed to… read more here.
Keywords: memantine neurological; disorders schizophrenia; neurological disorders; schizophrenia depression ... See more keywords
Attitudes of Catholic Priests Regarding the Participation of People with Schizophrenia and Depression in Religious Practices: Relationships with Prejudices and Community Size
Sign Up to like & getrecommendations! Published in 2022 at "Community Mental Health Journal"
DOI: 10.1007/s10597-022-00953-7
Abstract: This study investigated whether priests’ attitudes regarding individuals with schizophrenia and depression participating in religious practices varied in relation to priests’ adherence to prejudices about these mental disorders (MD). A sample of 559 Italian priests… read more here.
Keywords: schizophrenia depression; religious practices; community size;
Convergence and divergence of neurocognitive patterns in schizophrenia and depression
Sign Up to like & getrecommendations! Published in 2018 at "Schizophrenia Research"
DOI: 10.1016/j.schres.2017.06.004
Abstract: BACKGROUND Neurocognitive impairments are frequently observed in schizophrenia and major depressive disorder (MDD). However, it remains unclear whether reported neurocognitive abnormalities could objectively identify an individual as having schizophrenia or MDD. METHODS The current study… read more here.
Keywords: depression; neurocognitive patterns; convergence divergence; schizophrenia depression ... See more keywords
F107. CSF ABNORMALITIES IN SCHIZOPHRENIA AND DEPRESSION: PRELIMINARY RESULTS FROM A LARGE SCALE COHORT
Sign Up to like & getrecommendations! Published in 2018 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sby017.638
Abstract: Abstract Background CSF abnormalities and a neuroinflammatory pathophysiology have been discussed for affective and non-affective psychosis for more than 30-years. Recent studies pointed towards a specific phenotype of autoimmune-antibody mediated psychosis, but evidence is still… read more here.
Keywords: large scale; oligoclonal bands; csf; csf abnormalities ... See more keywords
A Machine Learning Model For Predicting Blood Concentration of Quetiapine in Patients With Schizophrenia and Depression Based on Real-World Data.
Sign Up to like & getrecommendations! Published in 2023 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.15734
Abstract: OBJECTIVE This study aimed to establish a prediction model of quetiapine concentration in patients with schizophrenia and depression, based on real-world data via machine learning techniques to assist clinical regimen decisions. METHODS A total of… read more here.
Keywords: schizophrenia depression; tdm; patients schizophrenia; concentration ... See more keywords
Using animal models for the studies of schizophrenia and depression: The value of translational models for treatment and prevention
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2022.935320
Abstract: Animal models of psychiatric disorders have been highly effective in advancing the field, identifying circuits related to pathophysiology, and identifying novel therapeutic targets. In this review, we show how animal models, particularly those based on… read more here.
Keywords: schizophrenia depression; models studies; animal models; using animal ... See more keywords
Decision Making under Risk in Patients Suffering from Schizophrenia or Depression
Sign Up to like & getrecommendations! Published in 2021 at "Brain Sciences"
DOI: 10.3390/brainsci11091178
Abstract: Studies have reported difficulties in decision making for patients with schizophrenia or depression. Here, we investigated whether there are differences between schizophrenia patients, depressed patients, and healthy individuals (HC) when decisions are to be made… read more here.
Keywords: decision; risk; decision making; schizophrenia patients ... See more keywords
Genetic Predisposition to Schizophrenia and Depressive Disorder Comorbidity
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13030457
Abstract: Background: Patients with schizophrenia have an increased risk of depressive disorders compared to the general population. The comorbidity between schizophrenia and depression suggests a potential coincidence of the pathophysiology and/or genetic predictors of these mental… read more here.
Keywords: genetic predictors; comorbidity; schizophrenia depression; schizophrenia ... See more keywords
New Atypical Antipsychotics in the Treatment of Schizophrenia and Depression
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810624
Abstract: Schizophrenia and depression are heterogeneous disorders. The complex pathomechanism of the diseases imply that medication responses vary across patients. Many psychotropic drugs are available but achieving optimal therapeutic effect can be challenging. The evidence correlates… read more here.
Keywords: schizophrenia depression; depression; new atypical; schizophrenia ... See more keywords