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Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.10.055
Abstract: D-Serine, an endogenous coagonist of N-methyl-d-aspartate receptors (NMDARs) at the glycine binding site, is synthesized by serine racemase (SR) through conversion of l-Serine. Dysregulation of SR/D-Serine and Disrupted-In-Schizophrenia-1 (DISC1) contributes to the pathogenesis of schizophrenia…
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Keywords:
serine racemase;
serine;
disc1 agglomerates;
schizophrenia disc1 ... See more keywords