Interaction of schizophrenia polygenic risk and cortisol level on pre-adolescent brain structure
Sign Up to like & getrecommendations! Published in 2019 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2018.12.231
Abstract: The etiology of schizophrenia is multi-factorial with early neurodevelopmental antecedents, likely to result from a complex interaction of genetic and environmental risk. However, few studies have examined how schizophrenia polygenic risk scores (PRS) are moderated… read more here.
Keywords: risk; schizophrenia; schizophrenia polygenic; brain ... See more keywords
O2.4. FUNCTIONAL CONNECTOME-WIDE ASSOCIATIONS OF SCHIZOPHRENIA POLYGENIC RISK
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DOI: 10.1093/schbul/sbaa028.009
Abstract: Abstract Background The relationships between schizophrenia polygenic risk and connectome-wide brain connectivity remain unclear. In particular, it is unknown whether and how schizophrenia polygenic risk would influence functional connectivity both at the connectome level and… read more here.
Keywords: risk; network; schizophrenia polygenic; connectome ... See more keywords
Association between psychiatric hospitalizations of patients with schizophrenia and polygenic risk scores based on genes with altered expression by antipsychotics
Sign Up to like & getrecommendations! Published in 2022 at "Acta Psychiatrica Scandinavica"
DOI: 10.1111/acps.13444
Abstract: To test whether a schizophrenia polygenic risk score (PRS) based on the subset of polymorphisms that affect brain expression of genes with altered expression by antipsychotics (exprAP PRS) is associated with psychiatric readmission of patients… read more here.
Keywords: schizophrenia polygenic; altered expression; polygenic risk; expression ... See more keywords