Increased thin-spine density in frontal cortex pyramidal neurons in a genetic rat model of schizophrenia-relevant features
Sign Up to like & getrecommendations! Published in 2021 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2021.01.006
Abstract: The cellular mechanisms altered during brain wiring leading to cognitive disturbances in neurodevelopmental disorders remain unknown. We have previously reported altered cortical expression of neurodevelopmentally regulated synaptic markers in a genetic animal model of schizophrenia-relevant… read more here.
Keywords: model schizophrenia; spine density; schizophrenia relevant; density ... See more keywords
The effects of preventative cannabidiol in a male neuregulin 1 mouse model of schizophrenia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.1010478
Abstract: Cannabidiol (CBD) is a non-intoxicating cannabinoid with antipsychotic-like properties, however it’s potential to prevent schizophrenia development has not been thoroughly investigated. Brain maturation during adolescence creates a window where CBD could potentially limit the development… read more here.
Keywords: mouse; schizophrenia relevant; cbd; nrg1 mutants ... See more keywords