Electrical Differentiation of Mesenchymal Stem Cells into Schwann‐Cell‐Like Phenotypes Using Inkjet‐Printed Graphene Circuits
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201601087
Abstract: Graphene-based materials (GBMs) have displayed tremendous promise for use as neurointerfacial substrates as they enable favorable adhesion, growth, proliferation, spreading, and migration of immobilized cells. This study reports the first case of the differentiation of… read more here.
Keywords: like phenotypes; differentiation mesenchymal; schwann cell; differentiation ... See more keywords
Sulfatase‐mediated manipulation of the astrocyte‐Schwann cell interface
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DOI: 10.1002/glia.23047
Abstract: Schwann cell (SC) transplantation following spinal cord injury (SCI) may have therapeutic potential. Functional recovery is limited however, due to poor SC interactions with host astrocytes and the induction of astrogliosis. Olfactory ensheathing cells (OECs)… read more here.
Keywords: sulfatase mediated; sulfatase; astrocyte; schwann cell ... See more keywords
Schwann cell‐specific deletion of the endosomal PI 3‐kinase Vps34 leads to delayed radial sorting of axons, arrested myelination, and abnormal ErbB2‐ErbB3 tyrosine kinase signaling
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23173
Abstract: The PI 3‐kinase Vps34 (Pik3c3) synthesizes phosphatidylinositol 3‐phosphate (PI3P), a lipid critical for both endosomal membrane traffic and macroautophagy. Human genetics have implicated PI3P dysregulation, and endosomal trafficking in general, as a recurring cause of… read more here.
Keywords: vps34; schwann cell; kinase; myelination ... See more keywords
The TSC1‐mTOR‐PLK axis regulates the homeostatic switch from Schwann cell proliferation to myelination in a stage‐specific manner
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DOI: 10.1002/glia.23449
Abstract: Proper peripheral myelination depends upon the balance between Schwann cell proliferation and differentiation programs. The serine/threonine kinase mTOR integrates various environmental cues to serve as a central regulator of cell growth, metabolism, and function. We… read more here.
Keywords: schwann; cell proliferation; schwann cell; mtor ... See more keywords
Modulation of Schwann cell homeostasis by the BAP1 deubiquitinase
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DOI: 10.1002/glia.24351
Abstract: Schwann cell programming during myelination involves transcriptional networks that activate gene expression but also repress genes that are active in neural crest/embryonic differentiation of Schwann cells. We previously found that a Schwann cell‐specific deletion of… read more here.
Keywords: bap1; schwann; injury; schwann cell ... See more keywords
Schwann cell‐specific RhoA knockout accelerates peripheral nerve regeneration via promoting Schwann cell dedifferentiation
Sign Up to like & getrecommendations! Published in 2023 at "Glia"
DOI: 10.1002/glia.24365
Abstract: Our previous studies indicated that RhoA knockdown or inhibition could alleviate the proliferation, migration, and differentiation of Schwann cells. However, the role of RhoA in Schwann cells during nerve injury and repair is still unknown.… read more here.
Keywords: schwann cells; schwann; nerve; rhoa ... See more keywords
Schwann cell precursors generate sympathoadrenal system during zebrafish development
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DOI: 10.1002/jnr.24909
Abstract: The autonomic portion of the peripheral nervous system orchestrates tissue homeostasis through direct innervation of internal organs, and via release of adrenalin and noradrenalin into the blood flow. The developmental mechanisms behind the formation of… read more here.
Keywords: cell precursors; chromaffin cells; system; schwann cell ... See more keywords
Oligodendrocyte precursors gain Schwann cell‐like phenotype and remyelinate axons upon engraftment into peripheral nerves
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2935
Abstract: The ability to treat large peripheral nerve injuries may be greatly advanced if an accessible source of human myelinating cells is identified, as it overcomes one of the major limitations of acellular or synthetic nerve… read more here.
Keywords: cell like; schwann cell; nerve; cell ... See more keywords
Scalable Differentiation and Dedifferentiation Assays Using Neuron-Free Schwann Cell Cultures.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7649-2_14
Abstract: This chapter describes protocols to establish simplified in vitro assays of Schwann cell (SC) differentiation in the absence of neurons. The assays are based on the capacity of isolated primary SCs to increase or decrease… read more here.
Keywords: dedifferentiation assays; schwann cell; differentiation; cell ... See more keywords
Live Imaging of Schwann Cell Development in Zebrafish.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7649-2_27
Abstract: The optical transparency of zebrafish larvae enables live imaging. Here we describe the methodology for live imaging and detail how to mount larvae for live imaging of Schwann cell development. read more here.
Keywords: imaging schwann; cell development; schwann cell; live imaging ... See more keywords
Schwann Cell and the Pathogenesis of Charcot-Marie-Tooth Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-32-9636-7_19
Abstract: Charcot-Marie-Tooth (CMT) disease is the most common hereditary neuropathy and genetically heterogeneous. CMT1 and CMTX are autosomal dominant and X-linked demyelinating neuropathies, respectively. CMT1A, CMT1B, and CMTX1 are the common forms of CMT, which are… read more here.
Keywords: marie tooth; charcot marie; disease; schwann cell ... See more keywords