Tissue-engineered in vitro modeling of the impact of Schwann cells in amyotrophic lateral sclerosis.
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.28083
Abstract: Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease affecting upper and lower motor neurons (MN). To investigate whether Schwann cells could be involved in the disease pathogenesis, we developed a tissue-engineered 3D in vitro… read more here.
Keywords: lateral sclerosis; engineered vitro; schwann cells; schwann ... See more keywords
Overexpression of P2X4 receptor in Schwann cells promotes motor and sensory functional recovery and remyelination via BDNF secretion after nerve injury
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DOI: 10.1002/glia.23527
Abstract: Of the seven P2X receptor subtypes, P2X4 receptor (P2X4R) is widely distributed in the central nervous system, including in neurons, astrocytes, and microglia. Accumulating evidence supports roles for P2X4R in the central nervous system, including… read more here.
Keywords: schwann; schwann cells; remyelination; p2x4r ... See more keywords
Piezo channels contribute to the regulation of myelination in Schwann cells
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DOI: 10.1002/glia.24251
Abstract: Peripheral nerves and Schwann cells have to sustain constant mechanical constraints, caused by developmental growth as well as stretches associated with movements of the limbs and mechanical compressions from daily activities. In Schwann cells, signaling… read more here.
Keywords: schwann cells; yap taz; schwann; regulation ... See more keywords
Human repair‐related Schwann cells adopt functions of antigen‐presenting cells in vitro
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DOI: 10.1002/glia.24257
Abstract: The plastic potential of Schwann cells (SCs) is increasingly recognized to play a role after nerve injury and in diseases of the peripheral nervous system. In addition, reports on the interaction between SCs and immune… read more here.
Keywords: repair related; antigen presenting; schwann cells; presenting cells ... See more keywords
Schwann cell‐specific RhoA knockout accelerates peripheral nerve regeneration via promoting Schwann cell dedifferentiation
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DOI: 10.1002/glia.24365
Abstract: Our previous studies indicated that RhoA knockdown or inhibition could alleviate the proliferation, migration, and differentiation of Schwann cells. However, the role of RhoA in Schwann cells during nerve injury and repair is still unknown.… read more here.
Keywords: schwann cells; schwann; nerve; rhoa ... See more keywords
Intraspinal Delivery of Schwann Cells for Spinal Cord Injury.
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DOI: 10.1007/978-1-4939-7649-2_31
Abstract: Cell transplant-mediated tissue repair of the damaged spinal cord is being tested in several clinical trials. The current candidates are neural stem cells, stromal cells, and autologous Schwann cells (aSC). Due to their peripheral origin… read more here.
Keywords: schwann cells; delivery; cord injury; spinal cord ... See more keywords
Derivation of Fate-Committed Schwann Cells from Bone Marrow Stromal Cells of Adult Rats.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7649-2_9
Abstract: Our goal is to derive phenotypically stable Schwann cells from bone marrow stromal cells (BMSCs) for use in transplantation studies of central/peripheral nerve injuries. With the adult rat as model, here we describe steps that… read more here.
Keywords: marrow stromal; schwann cells; stromal cells; cells bone ... See more keywords
Isolation and Purification of Primary Rodent Schwann Cells.
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DOI: 10.1007/978-1-4939-7862-5_7
Abstract: Schwann cells are the main glial cells of the peripheral nervous system (PNS) and play key roles in peripheral nerve development and function, including providing myelin that is essential for normal movement and sensation in… read more here.
Keywords: schwann cells; schwann; purification primary; isolation purification ... See more keywords
DRG Neuron/Schwann Cells Myelinating Cocultures.
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DOI: 10.1007/978-1-4939-7862-5_9
Abstract: Our understanding of the processes controlling peripheral nervous system myelination have been significantly benefited by the development of an in vitro myelinating culture system in which primary Schwann cells are cocultured together with primary sensory… read more here.
Keywords: schwann cells; cells myelinating; drg neuron; myelinating cocultures ... See more keywords
Anti-apoptotic Effect of Taurine on Schwann Cells Exposed to High Glucose In Vitro.
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DOI: 10.1007/978-981-13-8023-5_68
Abstract: It was reported that apoptosis of Schwann cells could increase in the diabetic rats. The studies showed that taurine inhibited apoptosis in a variety of cells. However, there were few reports on studying the protection… read more here.
Keywords: apoptosis; schwann cells; cells exposed; high glucose ... See more keywords
Prominence of nestin-expressing Schwann cells in bone marrow of patients with myelodysplastic syndromes with severe fibrosis
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DOI: 10.1007/s12185-018-02576-9
Abstract: Nestin-expressing stromal cells (NESCs) and Schwann cells in the bone marrow (BM) play crucial roles as a niche for normal hematopoietic stem cells in mice. It has been reported that both types of cells are… read more here.
Keywords: myelodysplastic syndromes; fibrosis; schwann cells; nestin expressing ... See more keywords