Architecture‐Engineered Electrospinning Cascade Regulates Spinal Microenvironment to Promote Nerve Regeneration
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202658
Abstract: The inflammatory cascade after spinal cord injury (SCI) causes necrotizing apoptosis of local stem cells, which limits nerve regeneration. Therefore, coordinating the inflammatory immune response and neural stem cell (NSC) functions is key to promoting… read more here.
Keywords: regeneration; sci; system; microenvironment ... See more keywords
Neuregulin‐1 positively modulates glial response and improves neurological recovery following traumatic spinal cord injury
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23150
Abstract: Spinal cord injury (SCI) results in glial activation and neuroinflammation, which play pivotal roles in the secondary injury mechanisms with both pro‐ and antiregeneration effects. Presently, little is known about the endogenous molecular mechanisms that… read more here.
Keywords: recovery following; injury; sci; spinal cord ... See more keywords
Quercetin reduces neural tissue damage and promotes astrocyte activation after spinal cord injury in rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26392
Abstract: Spinal cord injury (SCI) is lead to locomotor impairment because of neurological damage after following trauma. Quercetin (Que) has been confirmed to have a neuro‐protective effect during nerve damage processes. The purpose of this study… read more here.
Keywords: sci; astrocyte activation; activation; damage ... See more keywords
A potential entanglement between the spinal cord and hippocampus: Theta rhythm correlates with neurogenesis deficiency following spinal cord injury in male rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24719
Abstract: Cognitive deficits due to spinal cord injury (SCI) have been elucidated in both animals and humans with SCI. Such disorders may cause concomitant oscillatory changes in regions of the brain involving in cognition; a subject… read more here.
Keywords: theta; sci; theta rhythm; spinal cord ... See more keywords
Comparison of the effects of two therapeutic strategies based on olfactory ensheathing cell transplantation and repetitive magnetic stimulation after spinal cord injury in female mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24836
Abstract: Spinal cord injury (SCI) is a debilitating condition, which leads to a permanent loss of functions below the injury site. The events which take place after SCI are characterized by cellular death, release of inhibitory… read more here.
Keywords: sci; olfactory ensheathing; magnetic stimulation; transplantation ... See more keywords
Impact of injury duration on a sensorimotor functional network in complete spinal cord injury
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25069
Abstract: Connectivity changes after spinal cord injury (SCI) appear as dynamic post‐injury procedures. The present study aimed to investigate the alterations in the functional connectivity (FC) in different injury duration in complete SCI using resting‐state functional… read more here.
Keywords: sci; cord injury; sensorimotor; cortex ... See more keywords
Highest ambulatory speed using Lokomat gait training for individuals with a motor-complete spinal cord injury: a clinical pilot study
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-019-04189-5
Abstract: Background Motor impairment and loss of ambulatory function are major consequences of a spinal cord injury (SCI). Exoskeletons are robotic devices that allow SCI patients with limited ambulatory function to walk. The mean walking speed… read more here.
Keywords: sci; training; study; speed ... See more keywords
Neuroprotection of melatonin on spinal cord injury by activating autophagy and inhibiting apoptosis via SIRT1/AMPK signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Letters"
DOI: 10.1007/s10529-020-02939-5
Abstract: The effect of melatonin (MT) on spinal cord injury (SCI) has attracted increasing research attention. However, the specific role and molecular mechanism of MT on SCI have not been elucidated. An experiment was performed to… read more here.
Keywords: sci; sirt1 ampk; spinal cord; signaling pathway ... See more keywords
Electro-Acupuncture Inhibits p66Shc-Mediated Oxidative Stress to Facilitate Functional Recovery After Spinal Cord Injury
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-020-01609-5
Abstract: Oxidative stress is the core problem in improving secondary spinal cord injury (SCI). To investigate the effect of electro-acupuncture with different frequencies on neuroinflammation, oxidative stress injury, as well as related signaling pathways, male Sprague-Dawley… read more here.
Keywords: electro acupuncture; p66 shc; sci; oxidative stress ... See more keywords
Hypothalamic–pituitary–adrenal axis function in traumatic spinal cord injury-related neuropathic pain: a case–control study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-019-1002-9
Abstract: PurposeThis study aimed to investigate the hypothalamic–pituitary–adrenal (HPA) axis in spinal cord injury (SCI)-related neuropathic pain (NP) using dynamic adrenocorticotropic hormone (ACTH) stimulation tests.MethodsThis case–control study was conducted with 22 patients diagnosed with traumatic chronic… read more here.
Keywords: sci; study; neuropathic pain; cord injury ... See more keywords
Macrophage membrane-mediated targeted drug delivery for treatment of spinal cord injury regardless of the macrophage polarization states
Sign Up to like & getrecommendations! Published in 2021 at "Asian Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ajps.2021.03.005
Abstract: Targeted delivery of therapeutics for spinal cord injury (SCI) has been a long-term challenge due to the complexity of the pathological procession. Macrophage, as an immune cell, can selectively accumulate at the trauma site after… read more here.
Keywords: sci; delivery; macrophage; macrophage membrane ... See more keywords