mRNA Analysis of Frameshift Mutations with Stop Codon in the Last Exon: The Case of Hemoglobins Campania [α1 cod95 (−C)] and Sciacca [α1 cod109 (−C)]
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DOI: 10.3390/biomedicines9101390
Abstract: An insertion or deletion of a nucleotide (nt) in the penultimate or the last exon can result in a frameshift and premature termination codon (PTC), giving rise to an unstable protein variant, showing a dominant… read more here.
Keywords: frameshift; last exon; sciacca; sciacca cod109 ... See more keywords