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   Articles with "scid mice" as a keyword



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Unbiased transcriptomic analyses reveal distinct effects of immune deficiency in CNS function with and without injury

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recommendations! Published in 2018 at "Protein & Cell"

DOI: 10.1007/s13238-018-0559-y

Abstract: AbstractThe mammalian central nervous system (CNS) is considered an immune privileged system as it is separated from the periphery by the blood brain barrier (BBB). Yet, immune functions have been postulated to heavily influence the… read more here.

Keywords: scid mice; cns; without injury; function ... See more keywords
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Lack of tumorigenesis and protumorigenic activity of human umbilical cord mesenchymal stem cells in NOD SCID mice

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recommendations! Published in 2022 at "BMC Cancer"

DOI: 10.1186/s12885-022-09431-5

Abstract: Background The tumorigenesis of infused umbilical cord mesenchymal stem cells (UC-MSCs) is being preclinically evaluated. Methods We observed tumor formation in NOD SCID mice after a single subcutaneous injection of hUC-MSCs and the effect of… read more here.

Keywords: tumor; scid mice; nod scid; umbilical cord ... See more keywords
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Recombination activating gene-2null severe combined immunodeficient pigs and mice engraft human induced pluripotent stem cells differently

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recommendations! Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.20626

Abstract: This study comparatively investigated the transcriptional, physiological, and phenotypic differences of the immune disorder between severe combined immunodeficient (SCID) mouse and pig models. We discovered that the recombination activating gene-2 (Rag-2) SCID mice, but not… read more here.

Keywords: scid mice; scid pigs; rag scid; mice ... See more keywords
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Comparative Metabonomic Investigations of Schistosoma japonicum From SCID Mice and BALB/c Mice: Clues to Developmental Abnormality of Schistosome in the Immunodeficient Host

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recommendations! Published in 2019 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2019.00440

Abstract: The growth and development of schistosome has been affected in the immunodeficient hosts. But it remains unresolved about the molecular mechanisms involved in the development and reproduction regulation of schistosomes. This study tested and compared… read more here.

Keywords: metabolism; scid mice; worms scid; mice ... See more keywords
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Fast recovery of platelet production in NOD/SCID mice after transplantation with ex vivo expansion of megakaryocyte from cord blood CD34+ cells

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recommendations! Published in 2018 at "Journal of Cancer Research and Therapeutics"

DOI: 10.4103/0973-1482.193893

Abstract: Background: Cord blood transplantation (CBT) can be a life-saving procedure in the treatment of a broad variety of disorders, including hematologic, immune, and genetic diseases. However, delayed platelet recovery hinders the application of CBT. Purpose:… read more here.

Keywords: scid mice; transplantation; blood; nod scid ... See more keywords