Bezlotoxumab (BEZ) for Prevention of Clostridium Difficile Infection (CDI) Recurrence (rCDI): Outcomes in Patients with Substantial Renal Impairment (SRI)
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DOI: 10.1093/ofid/ofx163.962
Abstract: Abstract Background CDI in patients with SRI is harder to treat and is associated with higher recurrence. MODIFY I/II found that BEZ, a monoclonal antibody against C. difficile toxin B, is superior to placebo (PBO)… read more here.
Keywords: cdi; scientific advisor; speaker; sri ... See more keywords
1871. Identifying Time Periods of High and Low Vancomycin Use
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DOI: 10.1093/ofid/ofy210.1527
Abstract: Abstract Background A national goal has been set to decrease inappropriate antibiotic use by 2020. To quantify decreases in use, consumption metrics and benchmarking strategies are implicit. However, while tracking and reporting antimicrobial use is… read more here.
Keywords: advisor consulting; use; scientific advisor; vancomycin use ... See more keywords
2386. Efficacy of Lefamulin (LEF) vs. Moxifloxacin (MOX) Against Common Pathogens in Adults With Community-Acquired Bacterial Pneumonia (CABP): Results From the Phase 3 Lefamulin Evaluation Against Pneumonia (LEAP 1) Study
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DOI: 10.1093/ofid/ofy210.2039
Abstract: Abstract Background New CABP treatments with targeted activity and improved tolerability are needed. LEF, a novel pleuromutilin antibiotic that binds to a conserved region of the bacterial ribosome, is in development for IV or oral… read more here.
Keywords: consultant consulting; fee; employee; scientific advisor ... See more keywords
1019. Treatment Outcomes for Enterococcus faecium Bacteremia in Solid-Organ Transplant Patients: Implications for Daptomycin
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DOI: 10.1093/ofid/ofy210.856
Abstract: Abstract Background Optimal antimicrobial therapy for Enterococcus faecium (EFM) bacteremia in the solid-organ transplant (SOT) population is not well defined. Antimicrobial resistance, immunosuppression, and high mortality associated with EFM infections all pose serious threats. The… read more here.
Keywords: advisor consulting; scientific advisor; mortality; bacteremia ... See more keywords