Stem Cells: Scientific and Ethical Quandaries of a Personalized Approach to Parkinson's Disease
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DOI: 10.1002/mds.28187
Abstract: Parkinson’s disease (PD), the second most common neurodegenerative disorder after Alzheimer’s disease, is one of the most disabling and therapeutically challenging conditions. Although pharmacological therapy and deep brain stimulation often provide adequate symptomatic relief of… read more here.
Keywords: disease; motor; scientific ethical; parkinson disease ... See more keywords
Transwomen in elite sport: scientific and ethical considerations
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DOI: 10.1136/medethics-2018-105208
Abstract: The inclusion of elite transwomen athletes in sport is controversial. The recent International Olympic Committee (IOC) (2015) guidelines allow transwomen to compete in the women’s division if (amongst other things) their testosterone is held below… read more here.
Keywords: transwomen elite; sport scientific; elite sport; advantage ... See more keywords
Incentives and payments in pragmatic clinical trials: Scientific, ethical, and policy considerations
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DOI: 10.1177/17407745211048178
Abstract: Pragmatic clinical trials are increasingly used to generate knowledge about real-world clinical interventions. However, they involve some distinctive ethical and regulatory challenges. In this article, we examine a set of issues related to incentives and… read more here.
Keywords: trials scientific; pragmatic clinical; payments pragmatic; clinical trials ... See more keywords
Scientific, Ethical, and Practical Considerations for the Testing and Disclosure of Alzheimer Disease Biomarkers
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DOI: 10.1212/wnl.0000000000207199
Abstract: With the advent of promising, biomarker-directed, amyloid monoclonal antibody therapy for Alzheimer disease (AD),1 there is a need to understand the complex scientific, ethical, and practical implications related to biomarkers of neurodegenerative conditions,2 including how… read more here.
Keywords: alzheimer disease; scientific ethical; practical considerations; considerations testing ... See more keywords