The genetic architecture of multiple sclerosis
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DOI: 10.1038/s41591-019-0656-3
Abstract: A large-scale meta-analysis of multiple sclerosis (MS) genetic data identifies over 200 variants that are significantly associated with MS susceptibility. MS is a debilitating autoimmune disease that affects the central nervous system. Previous studies have… read more here.
Keywords: sclerosis; medicine; sclerosis genetic; multiple sclerosis ... See more keywords
The multifaceted role of kinases in amyotrophic lateral sclerosis: genetic, pathological and therapeutic implications
Sign Up to like & getrecommendations! Published in 2020 at "Brain"
DOI: 10.1093/brain/awaa022
Abstract: By reviewing recent findings on kinase function in ALS, Guo et al. show that kinases are implicated in ALS disease progression on three levels: a) genes encoding kinases are causal or risk genes in ALS;… read more here.
Keywords: kinases amyotrophic; role kinases; amyotrophic lateral; sclerosis genetic ... See more keywords