Deep learning with diffusion basis spectrum imaging for classification of multiple sclerosis lesions
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51037
Abstract: Multiple sclerosis (MS) lesions are heterogeneous with regard to inflammation, demyelination, axonal injury, and neuronal loss. We previously developed a diffusion basis spectrum imaging (DBSI) technique to better address MS lesion heterogeneity. We hypothesized that… read more here.
Keywords: basis spectrum; spectrum imaging; deep learning; multiple sclerosis ... See more keywords
Positron emission tomography with [18 F]-DPA-714 unveils a smoldering component in most multiple sclerosis lesions which drives disease progression.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of neurology"
DOI: 10.1002/ana.26657
Abstract: OBJECTIVE To determine the prognostic value of persisting neuroinflammation in multiple sclerosis (MS) lesions, we developed a 18kDa-translocator-protein-PET based classification of each lesion according to innate immune cell content and localization, and assessed the respective… read more here.
Keywords: dpa 714; multiple sclerosis; sclerosis lesions; progression ... See more keywords
Texture analysis in susceptibility-weighted imaging may be useful to differentiate acute from chronic multiple sclerosis lesions
Sign Up to like & getrecommendations! Published in 2020 at "European Radiology"
DOI: 10.1007/s00330-020-06995-3
Abstract: To evaluate the diagnostic performance of texture analysis (TA) applied on non-contrast-enhanced susceptibility-weighted imaging (SWI) to differentiate acute (enhancing) from chronic (non-enhancing) multiple sclerosis (MS) lesions. We analyzed 175 lesions from 58 patients with relapsing-remitting… read more here.
Keywords: differentiate acute; analysis; texture analysis; multiple sclerosis ... See more keywords
An Advanced MRI Multi-Modalities Segmentation Methodology Dedicated to Multiple Sclerosis Lesions Exploration and Differentiation
Sign Up to like & getrecommendations! Published in 2017 at "IEEE Transactions on NanoBioscience"
DOI: 10.1109/tnb.2017.2763246
Abstract: Multiple sclerosis (MS) is one of the most common neurological diseases in young people. This paper dealt with an automatic biomedical aided tool involving volumetric segmentation of multiple sclerosis lesions. To meet this challenge, our… read more here.
Keywords: methodology; segmentation; multiple sclerosis; sclerosis lesions ... See more keywords
Expression of the Antioxidative Enzyme Peroxiredoxin 2 in Multiple Sclerosis Lesions in Relation to Inflammation
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18040760
Abstract: Multiple sclerosis is a chronic inflammatory disease of the central nervous system, characterized by demyelination and axonal damage as well as neuronal degeneration. Since oxygen-derived free radicals are an important factor leading to tissue damage… read more here.
Keywords: inflammation; sclerosis lesions; multiple sclerosis; expression ... See more keywords