Sclerostin deficiency modifies the development of CKD-MBD in mice.
Sign Up to like & getrecommendations! Published in 2018 at "Bone"
DOI: 10.1016/j.bone.2017.11.015
Abstract: Sclerostin is a soluble antagonist of canonical Wnt signaling and a strong inhibitor of bone formation. We present experimental data on the role of sclerostin in chronic kidney disease - bone mineral disorder (CKD-MBD). METHODS… read more here.
Keywords: ckd mbd; bone; sclerostin deficiency; mice ... See more keywords
Sclerostin deficiency effectively promotes bone morphogenetic protein-2-induced ectopic bone formation.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of periodontal research"
DOI: 10.1111/jre.13134
Abstract: BACKGROUND AND OBJECTIVE Severe periodontitis causes alveolar bone resorption, resulting in tooth loss. Developments of tissue regeneration therapy that can restore alveolar bone mass are desired for periodontal disease. The application of bone morphogenetic protein-2… read more here.
Keywords: induced ectopic; sclerostin deficiency; bone; bmp induced ... See more keywords