Relationship between plasma levels of sclerostin, calcium–phosphate disturbances, established markers of bone turnover, and inflammation in haemodialysis patients
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DOI: 10.1007/s11255-018-2050-3
Abstract: PurposeData concerning the relation between increased levels of circulating sclerostin (a physiological inhibitor of bone formation) and bone turnover in patients with chronic renal failure (CRF) are limited. Therefore, the aim of this study was… read more here.
Keywords: sclerostin levels; calcium phosphate; levels sclerostin; bone turnover ... See more keywords
Serum Sclerostin Levels and Mortality in Hemodialysis Patients: An 8-Year Prospective Study
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DOI: 10.1159/000528795
Abstract: Introduction: Sclerostin is an osteocyte-derived inhibitor of bone formation and is increased in kidney failure. Sclerostin might be involved in the pathogenesis of vascular calcification, but few studies have examined the association between sclerostin and… read more here.
Keywords: serum sclerostin; sclerostin; mortality; sclerostin levels ... See more keywords
SUN-537 Progesterone Therapy and Serum Sclerostin Levels in Healthy Menopausal Women: A 3-month Randomized, Placebo Controlled Clinical Trial
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DOI: 10.1210/js.2019-sun-537
Abstract: Abstract Sclerostin is an osteocyte-produced glycoprotein that inhibits the WNT/β-catenin pathway essential for bone formation. Sclerostin was postulated to relate to normal bone metabolism in 2001; we still have an incomplete understanding of its regulation.… read more here.
Keywords: serum sclerostin; sclerostin; month; progesterone ... See more keywords
Sclerostin levels predict cardiovascular mortality in long-term hemodialysis patients: a prospective observational cohort study.
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DOI: 10.33549/physiolres.934034
Abstract: Sclerostin is a protein which is involved in bone metabolism and probably also in vessel wall function. This prospective observational cohort study evaluated the prognostic significance of sclerostin in hemodialysis (HD) patients. In total, 106… read more here.
Keywords: sclerostin levels; cardiovascular mortality; prospective observational; sclerostin ... See more keywords
Exploring the Role of Sclerostin as a Biomarker of Cardiovascular Disease and Mortality: A Scoping Review
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DOI: 10.3390/ijerph192315981
Abstract: Sclerostin is most recognized for its role in controlling bone formation; however, it is also expressed in the heart, aorta, coronary, and peripheral arteries. Human studies have associated high circulating sclerostin levels with the presence… read more here.
Keywords: review; sclerostin; sclerostin levels; association ... See more keywords
Decreased Serum Level of Sclerostin in Older Adults with Sarcopenia
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DOI: 10.3803/enm.2022.1428
Abstract: Background Although muscles and bones interact with each other through various secretory factors, the role of sclerostin, an osteocyte-secreted factor, on muscle metabolism has not been well studied. We investigated the levels of serum sclerostin… read more here.
Keywords: older adults; serum sclerostin; sclerostin; muscle ... See more keywords
Does oxidative status affect serum sclerostin levels in patients with type 2 diabetes mellitus?
Sign Up to like & getrecommendations! Published in 2023 at "Folia medica"
DOI: 10.3897/folmed.65.e72953
Abstract: INTRODUCTION Sclerostin is a glycoprotein known as a negative regulator of bone formation, predominantly expressed by mature osteocytes. There is no causative evidence information on the role of sclerostin in the pathogenesis of type 2… read more here.
Keywords: oxidative status; serum sclerostin; sclerostin; type diabetes ... See more keywords