SCM-198 Prevents Endometriosis by Reversing Low Autophagy of Endometrial Stromal Cell via Balancing ERα and PR Signals
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DOI: 10.3389/fendo.2022.858176
Abstract: Background Endometriosis (EMS), an endocrine-related inflammatory disease, is characterized by estrogen and progesterone imbalance in ectopic lesions. However, its pathogenic mechanism has not been fully elucidated. While SCM-198 is the synthetic form of leonurine and… read more here.
Keywords: scm 198; inflammation; estrogen; eescs ... See more keywords
SCM-198 Alleviates Endometriosis by Suppressing Estrogen-ERα mediated Differentiation and Function of CD4+CD25+ Regulatory T Cells
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DOI: 10.7150/ijbs.68224
Abstract: Background: Endometriosis (EMS), a typical endocrine immune disorder, associates with dramatically increased estrogen production and disorganized immune response in ectopic focus. Peritoneal regulatory T cells (Tregs) expansion in women with EMS and their pathogenic role… read more here.
Keywords: scm 198; estrogen; regulatory cells; alleviates endometriosis ... See more keywords