Abstract 4432: scMAGeCK links genotypes with multiple phenotypes in single-cell CRISPR screens
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DOI: 10.1158/1538-7445.am2020-4432
Abstract: We present scMAGeCK, a computational framework to identify genomic elements associated with multiple expression-based phenotypes in CRISPR/Cas9 functional screening that uses single-cell RNA-seq as readout. scMAGeCK outperforms existing methods, identifies genes and enhancers with known… read more here.
Keywords: single cell; cell; cell crispr; scmageck links ... See more keywords