Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide
Sign Up to like & getrecommendations! Published in 2022 at "Europace"
DOI: 10.1093/europace/euac218
Abstract: Abstract Aims Atrial fibrillation (AF) is the most common cardiac arrhythmia. Pathogenic variants in genes encoding ion channels are associated with familial AF. The point mutation M1875T in the SCN5A gene, which encodes the α-subunit… read more here.
Keywords: mutation; sodium current; sodium; scn5a m1875t ... See more keywords