Clinical features and functional analysis of novel SCN9A variants causing congenital insensitivity to pain.
Sign Up to like & getrecommendations! Published in 2025 at "Pain"
DOI: 10.1097/j.pain.0000000000003628
Abstract: ABSTRACT Pain perception is a fundamental protective mechanism that enables us to detect noxious stimuli. With a focus on finding treatments for pain, the molecular mechanisms and key players involved in pain perception are currently… read more here.
Keywords: insensitivity pain; scn9a; insensitivity; congenital insensitivity ... See more keywords
Letter regarding “ SCN9A variant in a family of mixed breed dogs with congenital insensitivity to pain”—Navigating the pathogenicity of candidate gene mutations: Spotlight on paralog Nav genes
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Veterinary Internal Medicine"
DOI: 10.1111/jvim.16708
Abstract: Dear Editors, We read the recent publication by Dr. Gutierrez-Quintana et al. titled “SCN9A variant in a family of mixed breed dogs with congenital insensitivity to pain” with great interest. While mutations in voltage-gated sodium… read more here.
Keywords: nav1 r921c; scn9a; insensitivity pain; congenital insensitivity ... See more keywords