Timing of the First Cleavage and In Vitro Developmental Potential of Bovine Somatic Cell Nuclear Transfer Embryos Activated by Different Protocols.
Sign Up to like & getrecommendations! Published in 2019 at "Cellular reprogramming"
DOI: 10.1089/cell.2019.0074
Abstract: The objective of this study was to examine the relationship between the timing of the first cleavage and in vitro development of somatic cell nuclear transfer (SCNT) embryos produced by different activation protocols. SCNT embryos… read more here.
Keywords: scnt embryos; timing first; group; first cleavage ... See more keywords
Effects of Trichostatin A on the Timing of the First Cleavage and In Vitro Developmental Potential of Bovine Somatic Cell Nuclear Transfer Embryos.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular reprogramming"
DOI: 10.1089/cell.2022.0003
Abstract: This study examined the relationship between the timing of the first cleavage and in vitro development of bovine somatic cell nuclear transfer (SCNT) embryos treated with trichostatin A (TSA). SCNT embryos were visually assessed at… read more here.
Keywords: first cleavage; embryos; timing first; scnt embryos ... See more keywords
Reprogramming barriers in bovine cells nuclear transfer revealed by single‐cell RNA‐seq analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17505
Abstract: Many progresses have recently been achieved in animal somatic cell nuclear transfer (SCNT). However, embryos derived from SCNT rarely result in live births. Single‐cell RNA sequencing (scRNA‐seq) can be used to investigate the development details… read more here.
Keywords: scnt embryos; cell; nuclear transfer; transfer ... See more keywords
Single nucleolus precursor body formation in the pronucleus of mouse zygotes and SCNT embryos
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0202663
Abstract: Mammalian oocytes and zygotes have nucleoli that are transcriptionally inactive and structurally distinct from nucleoli in somatic cells. These nucleoli have been termed nucleolus precursor bodies (NPBs). Recent research has shown that NPBs are important… read more here.
Keywords: scnt embryos; pronucleus; nucleolus precursor; formation ... See more keywords
Melatonin accelerates the developmental competence and telomere elongation in ovine SCNT embryos
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0267598
Abstract: SCNT embryos suffer from poor developmental competence (both in vitro and in vivo) due to various defects such as oxidative stress, incomplete epigenetic reprogramming, and flaws in telomere rejuvenation. It is very promising to ameliorate… read more here.
Keywords: scnt embryos; ovine scnt; melatonin; scnt ... See more keywords