The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart
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DOI: 10.1093/hmg/ddx344
Abstract: Abstract SCO1 is a ubiquitously expressed, mitochondrial protein with essential roles in cytochrome c oxidase (COX) assembly and the regulation of copper homeostasis. SCO1 patients present with severe forms of early onset disease, and ultimately… read more here.
Keywords: heart; sco1stm stm; copper homeostasis; copper ... See more keywords