Neuroprotective effects of 20(S)‐protopanaxatriol (PPT) on scopolamine‐induced cognitive deficits in mice
Sign Up to like & getrecommendations! Published in 2018 at "Phytotherapy Research"
DOI: 10.1002/ptr.6044
Abstract: 20(S)‐protopanaxatriol (PPT), one of the ginsenosides from Panax ginseng, has been reported to have neuroprotective effects and to improve memory. The present study was designed to investigate the protective effect of PPT on scopolamine‐induced cognitive… read more here.
Keywords: scopolamine; neuroprotective effects; protopanaxatriol ppt; induced cognitive ... See more keywords
Neuroprotective effects of total alkaloids fraction of Huperzia serrata on scopolamine‐induced neurodegenerative animals
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7602
Abstract: Huperzia serrata contains Huperzine A (HupA)—an alkaloid used to treat cognitive dysfunction. In this study, we used the total alkaloids (HsAE) to investigate their potential in managing cognitive impairment in comparison with HupA. The antioxidant… read more here.
Keywords: huperzia serrata; total alkaloids; scopolamine; scopolamine induced ... See more keywords
Neuroprotection of SAK3 on scopolamine-induced cholinergic dysfunction in human neuroblastoma SH-SY5Y cells
Sign Up to like & getrecommendations! Published in 2020 at "Cytotechnology"
DOI: 10.1007/s10616-019-00366-7
Abstract: Alzheimer’s disease (AD) is the most common type of senile dementia. A number of factors have been proposed regarding pathology of AD, such as presence of β-amyloid, and cholinergic and oxidative stress. SAK3 (ethyl 8′-methyl-2′,5-dioxo-2-piperidin-1-ylspiro[cyclopentene-3,3′-imidazo[1,2-a]pyridine]-1-carboxylate)… read more here.
Keywords: scopolamine; human neuroblastoma; neuroblastoma sy5y; scopolamine induced ... See more keywords
Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroimmune Pharmacology"
DOI: 10.1007/s11481-018-9824-3
Abstract: AbstractCognitive decline and memory impairment induced by oxidative brain damage are the critical pathological hallmarks of Alzheimer’s disease (AD). Based on the potential neuroprotective effects of melatonin, we here explored the possible underlying mechanisms of… read more here.
Keywords: melatonin; scopolamine induced; memory; oxidative stress ... See more keywords
Cortico-Hippocampal Memory Enhancing Activity of Hesperetin on Scopolamine-Induced Amnesia in Mice: Role of Antioxidant Defense Systems, Cholinergic Neurotransmission and Expression of BDNF
Sign Up to like & getrecommendations! Published in 2019 at "IBRO Reports"
DOI: 10.1016/j.ibror.2019.09.051
Abstract: Alzheimer disease (AD) is an age related neurodegenerative disease causing severe cognitive and memory decline in elderly people. Flavonoids play neuroprotective role by inhibiting and/or modifying the self-assembly of the amyloid-β (Aβ) or tau peptide… read more here.
Keywords: scopolamine; scopolamine induced; role; antioxidant defense ... See more keywords
Cornuside ameliorates cognitive impairments in scopolamine induced AD mice: Involvement of neurotransmitter and oxidative stress.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2022.115252
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Cornus officinalis Sieb. et Zucc., traditional Chinese medicine, has been widely used in the treatment of dementia. Cornel iridoid glycosides of Cornus officinalis is therapeutic to Alzheimer's disease (AD), while its pharmacodynamic material… read more here.
Keywords: test; induced mice; scopolamine induced; oxidative stress ... See more keywords
Protective effects of SGB121, ginsenoside F1-enriched ginseng extract, on scopolamine-induced cytotoxicity and memory impairments
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2020.104165
Abstract: Abstract Ginsenosides have been reported to improve memory impairments. However, the effects of metabolized minor ginsenosides on neuronal damage and cognitive function remain unclear. We investigated the effects of SGB121, ginsenoside F1 enriched ginseng extract,… read more here.
Keywords: scopolamine; effects sgb121; scopolamine induced; sgb121 ginsenoside ... See more keywords
Lithium prevents scopolamine-induced memory impairment in zebrafish
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.11.010
Abstract: We examined whether lithium carbonate (Li2CO3, 100mg/L) is able to prevent memory impairment induced by scopolamine. Moreover, we evaluated the effects of lithium on anxiety-like behavior and acetylcholinesterase activity in adult zebrafish. We demonstrated that… read more here.
Keywords: memory impairment; lithium prevents; scopolamine induced; memory ... See more keywords
d-Cycloserine reverses scopolamine-induced object and place memory deficits in a spontaneous recognition paradigm in rats
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2019.172798
Abstract: d-Cycloserine (DCS) is a partial agonist of the glutamatergic N-methyl-d-aspartate (NMDA) receptor-associated glycine site, and it prevents the amnesic effects of the muscarinic receptor antagonist scopolamine in various memory tests in rodents. In the present… read more here.
Keywords: cycloserine reverses; dcs; recognition; scopolamine induced ... See more keywords
Sea Cucumber Peptides Attenuated the Scopolamine-Induced Memory Impairment in Mice and Rats and the Underlying Mechanism.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c06475
Abstract: Social stress and unhealthy diets lead to memory impairment, triggering health problems. This study aimed to determine the mitigating effect and regulation mechanism of sea cucumber peptides (SCP) against memory impairment. Here, scopolamine-induced memory impairment… read more here.
Keywords: memory impairment; induced memory; memory; scopolamine induced ... See more keywords
Arginine-Containing Peptides Derived from Walnut Protein Against Cognitive and Memory Impairment in Scopolamine-Induced Zebrafish: Design, Release, and Neuroprotection.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c05104
Abstract: The purpose of this study was to investigate the neuroprotective effect of Arg-containing peptides from walnut storage protein sequences in scopolamine-induced zebrafish and further to validate the potential neuroprotection of Arg-containing peptide enriched walnut hydrolysates… read more here.
Keywords: neuroprotection; arg containing; induced zebrafish; scopolamine induced ... See more keywords