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Published in 2017 at "JAMA Cardiology"
DOI: 10.1001/jamacardio.2017.2498
Abstract: Importance Besides age, other discriminators of atherosclerotic cardiovascular disease (ASCVD) risk are needed in older adults. Objectives To examine the predictive ability of coronary artery calcium (CAC) score vs age for incident ASCVD and how…
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Keywords:
risk;
age;
coronary artery;
artery calcium ... See more keywords
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Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.1781
Abstract: Importance Transthyretin amyloid cardiomyopathy (ATTR-CM) is a form of heart failure (HF) with preserved ejection fraction (HFpEF). Technetium Tc 99m pyrophosphate scintigraphy (PYP) enables ATTR-CM diagnosis. It is unclear which patients with HFpEF have sufficient…
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Keywords:
validation;
prevalence;
ejection fraction;
risk ... See more keywords
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Published in 2020 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2020.8501
Abstract: Importance To date, few studies have examined the extent to which polygenic single-nucleotide variation (SNV) (formerly single-nucleotide polymorphism) scores modify risk for carriers of pathogenic variants (PVs) in breast cancer susceptibility genes. In previous reports,…
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Keywords:
risk;
breast cancer;
polygenic risk;
cancer ... See more keywords
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Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.10552
Abstract: Key Points Question Can a novel clinical scoring system predict poor neurocognitive outcomes after acute carbon monoxide poisoning? Findings This prognostic study developed and externally validated a prediction model including 5 risk factors associated with…
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Keywords:
score;
monoxide poisoning;
carbon monoxide;
poor neurocognitive ... See more keywords
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Published in 2017 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2016.4491
Abstract: Importance Robust collateral blood vessels have been associated with better neurologic outcome following acute ischemic stroke (AIS). The most commonly used methods for identifying collaterals are contrast-based angiographic imaging techniques, which are not possible in…
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Keywords:
collateral;
outcome;
mrs;
association ... See more keywords
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Published in 2017 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2017.2459
Abstract: Importance Continuous electroencephalography (EEG) use in critically ill patients is expanding. There is no validated method to combine risk factors and guide clinicians in assessing seizure risk. Objective To use seizure risk factors from EEG…
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Keywords:
score score;
seizure risk;
risk;
model ... See more keywords
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Published in 2018 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.5524
Abstract: Importance Multiple molecular signatures are available for managing estrogen receptor (ER)–positive breast cancer but with little direct comparative information to guide the patient’s choice. Objective To conduct a within-patient comparison of the prognostic value of…
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Keywords:
information;
breast;
positive breast;
breast cancer ... See more keywords
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Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2023.0181
Abstract: Importance Patients with early-stage ERBB2 (formerly HER2)-positive breast cancer (ERBB2+ BC) who experience a pathologic complete response (pCR) after receiving neoadjuvant therapy have favorable survival outcomes. Predicting the likelihood of pCR may help optimize neoadjuvant…
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Keywords:
her2dx assay;
her2dx pcr;
pcr score;
pcr ... See more keywords
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Published in 2020 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2020.2974
Abstract: Importance During the coronavirus disease 2019 (COVID-19) pandemic, eye care professionals caring for patients with sight-threatening diseases, such as glaucoma, have had to determine whether some patient appointments could safely get postponed, weighing the risk…
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Keywords:
risk;
data repository;
ophthalmology;
morbidity ... See more keywords
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Published in 2017 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2017.2352
Abstract: Importance The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) uses the Sequential Organ Failure Assessment (SOFA) score to grade organ dysfunction in adult patients with suspected infection. However, the SOFA score is…
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Keywords:
sepsis;
ill children;
psofa;
critically ill ... See more keywords
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Published in 2021 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2021.1559
Abstract: Importance Postpartum depression (PPD) is one of the most common medical complications during and after pregnancy, negatively affecting both mother and child. Objective To demonstrate the efficacy and safety of zuranolone, a neuroactive steroid γ-aminobutyric…
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Keywords:
clinical trial;
depression;
zuranolone;
placebo ... See more keywords