Saddlepoint approximations to score test statistics in logistic regression for analyzing genome-wide association studies.
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DOI: 10.1002/sim.9746
Abstract: We investigate saddlepoint approximations of tail probabilities of the score test statistic in logistic regression for genome-wide association studies. The inaccuracy in the normal approximation of the score test statistic increases with increasing imbalance in… read more here.
Keywords: saddlepoint approximations; genome wide; logistic regression; score test ... See more keywords
Online profile monitoring for surgical outcomes using a weighted score test
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DOI: 10.1080/00224065.2018.1404329
Abstract: ABSTRACT In the past decade, risk-adjusted control charts have been widely used to monitor surgical outcomes. However, most existing approaches focus on monitoring shifts in location parameters and may not be able to detect a… read more here.
Keywords: online profile; profile monitoring; weighted score; surgical outcomes ... See more keywords
Genetic association tests in family samples for multi-category phenotypes
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DOI: 10.1186/s12864-021-08107-x
Abstract: Background Advancements in statistical methods and sequencing technology have led to numerous novel discoveries in human genetics in the past two decades. Among phenotypes of interest, most attention has been given to studying genetic associations… read more here.
Keywords: multi category; family samples; score test; family ... See more keywords