Biochemical Characterization of HL-7 and HL-10 Peptides Identified from Scorpion Venom of Hemiscorpius lepturus
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-017-9625-1
Abstract: In this study, the scorpion venom of H. lepturus was fractionized by reversed phase high-pressure liquid chromatography (RP-HPLC). The sequences of two peptide fractions were identified by tandem mass spectrometry and named as HL-10 (AFPYYGHHLG)… read more here.
Keywords: scorpion venom; identified scorpion; characterization peptides; biochemical characterization ... See more keywords
Scorpion Venom–Toxins that Aid in Drug Development: A Review
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-018-9721-x
Abstract: Scorpion venom components have multifaceted orientation against bacterial, viral, fungal infections and other neuronal disorders. They can modulate the ion channels (K+, Na+, Cl−, Ca2+) of our body and this concept has been hypothesized in… read more here.
Keywords: scorpion venom; venom; venom components; drug ... See more keywords
Development of a new approach of immunotherapy against scorpion envenoming: Avian IgYs an alternative to equine IgGs
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.06.013
Abstract: &NA; Antivenom treatment has been largely used against scorpion stings. Despite their efficacy, the use of mammalian antivenoms may cause adverse effects due to the immune system activation. IgYs from hyperimmunized laying hens against venoms… read more here.
Keywords: scorpion venom; alternative equine; igys; scorpion ... See more keywords
Detection of scorpion venom by optical circular dichroism method.
Sign Up to like & getrecommendations! Published in 2021 at "Scientific reports"
DOI: 10.1038/s41598-021-95493-7
Abstract: Various efforts have been made to detect minimum amounts of any toxic materials in water or the neurotoxic effect of venom (Odontobuthus Doriae Scorpion) in the human's blood serum nerve by high-sensitivity, accurate, and low-cost… read more here.
Keywords: scorpion venom; detection scorpion; neurotoxic effect; scorpion ... See more keywords
Boosting curcumin activity against human prostatic cancer PC3 cells by utilizing scorpion venom conjugated phytosomes as promising functionalized nanovesicles
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2048133
Abstract: Abstract Prostate cancer (PC) is emerging as one of the leading causes of mortality and morbidity worldwide. Curcumin (CUR) is a well-known phytochemical, and scorpion venom (SV) is a natural peptide with proven anticancer properties.… read more here.
Keywords: prostatic cancer; human prostatic; pc3 cells; scorpion venom ... See more keywords
Nontoxic fraction of scorpion venom reduces bacterial growth and inflammatory response in a mouse model of infection
Sign Up to like & getrecommendations! Published in 2019 at "Toxin Reviews"
DOI: 10.1080/15569543.2019.1614064
Abstract: Abstract This study aims to investigate the antimicrobial activity of Androctonus australis hector (Aah) scorpion venom and its nontoxic fraction. Obtained results show that venom inhibits the proliferation of both Gram-positive and Gram-negative bacteria via… read more here.
Keywords: scorpion venom; model infection; bacterial growth; nontoxic fraction ... See more keywords
A Novel Defensin-Like Peptide Associated with Two Other New Cationic Antimicrobial Peptides in Transcriptome of the Iranian Scorpion Venom
Sign Up to like & getrecommendations! Published in 2017 at "Iranian Biomedical Journal"
DOI: 10.18869/acadpub.ibj.21.3.190
Abstract: Introduction: Scorpion venom is a source of bioactive peptides, and some antimicrobial peptides (AMPs) have been found in the venom gland of scorpions. Therefore, the discovery of new anti-infective agents is an essential need to… read more here.
Keywords: scorpion venom; new cationic; iranian scorpion; scorpion ... See more keywords
Therapeutic Potential of Bee and Scorpion Venom Phospholipase A2 (PLA2): A Narrative Review
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Medical Sciences"
DOI: 10.30476/ijms.2021.88511.1927
Abstract: Venomous arthropods such as scorpions and bees form one of the important groups with an essential role in medical entomology. Their venom possesses a mixture of diverse compounds, such as peptides, some of which have… read more here.
Keywords: pla2; venom; phospholipase pla2; bee scorpion ... See more keywords
Scorpion Venom Antimicrobial Peptides Induce Caspase-1 Dependant Pyroptotic Cell Death
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.788874
Abstract: Within the last decade, several peptides have been identified according to their ability to inhibit the growth of microbial pathogens. These antimicrobial peptides (AMPs) are a part of the innate immune system of all living… read more here.
Keywords: cell death; cell; antimicrobial peptides; scorpion venom ... See more keywords
Scorpion Venom Heat–Resistant Synthesized Peptide Increases Stress Resistance and Extends the Lifespan of Caenorhabditis elegans via the Insulin/IGF-1-Like Signal Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.919269
Abstract: Improving healthy life expectancy by targeting aging-related pathological changes has been the spotlight of geroscience. Scorpions have been used in traditional medicine in Asia and Africa for a long time. We have isolated heat-resistant peptides… read more here.
Keywords: heat resistant; venom heat; caenorhabditis elegans; heat ... See more keywords
Strengthening Anti-Glioblastoma Effect by Multi-Branched Dendrimers Design of a Scorpion Venom Tetrapeptide
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27030806
Abstract: Glioblastoma is the most aggressive and invasive form of central nervous system tumors due to the complexity of the intracellular mechanisms and molecular alterations involved in its progression. Unfortunately, current therapies are unable to stop… read more here.
Keywords: effect; branched aats; multi branched; u87 cells ... See more keywords