Biochemical Characterization of HL-7 and HL-10 Peptides Identified from Scorpion Venom of Hemiscorpius lepturus
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-017-9625-1
Abstract: In this study, the scorpion venom of H. lepturus was fractionized by reversed phase high-pressure liquid chromatography (RP-HPLC). The sequences of two peptide fractions were identified by tandem mass spectrometry and named as HL-10 (AFPYYGHHLG)… read more here.
Keywords: scorpion venom; identified scorpion; characterization peptides; biochemical characterization ... See more keywords
Scorpion Venom–Toxins that Aid in Drug Development: A Review
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DOI: 10.1007/s10989-018-9721-x
Abstract: Scorpion venom components have multifaceted orientation against bacterial, viral, fungal infections and other neuronal disorders. They can modulate the ion channels (K+, Na+, Cl−, Ca2+) of our body and this concept has been hypothesized in… read more here.
Keywords: scorpion venom; venom; venom components; drug ... See more keywords
Development of a new approach of immunotherapy against scorpion envenoming: Avian IgYs an alternative to equine IgGs
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.06.013
Abstract: &NA; Antivenom treatment has been largely used against scorpion stings. Despite their efficacy, the use of mammalian antivenoms may cause adverse effects due to the immune system activation. IgYs from hyperimmunized laying hens against venoms… read more here.
Keywords: scorpion venom; alternative equine; igys; scorpion ... See more keywords
Detection of scorpion venom by optical circular dichroism method.
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DOI: 10.1038/s41598-021-95493-7
Abstract: Various efforts have been made to detect minimum amounts of any toxic materials in water or the neurotoxic effect of venom (Odontobuthus Doriae Scorpion) in the human's blood serum nerve by high-sensitivity, accurate, and low-cost… read more here.
Keywords: scorpion venom; detection scorpion; neurotoxic effect; scorpion ... See more keywords
Boosting curcumin activity against human prostatic cancer PC3 cells by utilizing scorpion venom conjugated phytosomes as promising functionalized nanovesicles
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DOI: 10.1080/10717544.2022.2048133
Abstract: Abstract Prostate cancer (PC) is emerging as one of the leading causes of mortality and morbidity worldwide. Curcumin (CUR) is a well-known phytochemical, and scorpion venom (SV) is a natural peptide with proven anticancer properties.… read more here.
Keywords: prostatic cancer; human prostatic; pc3 cells; scorpion venom ... See more keywords
Nontoxic fraction of scorpion venom reduces bacterial growth and inflammatory response in a mouse model of infection
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DOI: 10.1080/15569543.2019.1614064
Abstract: Abstract This study aims to investigate the antimicrobial activity of Androctonus australis hector (Aah) scorpion venom and its nontoxic fraction. Obtained results show that venom inhibits the proliferation of both Gram-positive and Gram-negative bacteria via… read more here.
Keywords: scorpion venom; model infection; bacterial growth; nontoxic fraction ... See more keywords
Behavioral, biochemical and histopathological alterations induced in Swiss mice by Buthus boumalenii scorpion venom
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DOI: 10.1080/15569543.2024.2346164
Abstract: Abstract The yellow scorpion, Buthus boumalenii, has long been recognized as a potentially dangerous species endemic to Morocco. However, there is currently no data on the in vivo toxicity or effects of Buthus boumalenii venom,… read more here.
Keywords: scorpion venom; buthus boumalenii; boumalenii scorpion; scorpion ... See more keywords
Scorpion venom heat‐resistant synthetic peptide improves cognitive dysfunction of APP/PS1 mice through microglial retromer complex
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DOI: 10.1111/bph.70124
Abstract: The abnormal accumulation of amyloid‐β (Aβ) in the brain is a characteristic pathological change observed in patients with Alzheimer's disease (AD). Microglial phagocytosis, dependent on recycling through the retromer complex and cell membrane‐bound receptors, plays… read more here.
Keywords: heat resistant; scorpion venom; retromer; resistant synthetic ... See more keywords
A Novel Defensin-Like Peptide Associated with Two Other New Cationic Antimicrobial Peptides in Transcriptome of the Iranian Scorpion Venom
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DOI: 10.18869/acadpub.ibj.21.3.190
Abstract: Introduction: Scorpion venom is a source of bioactive peptides, and some antimicrobial peptides (AMPs) have been found in the venom gland of scorpions. Therefore, the discovery of new anti-infective agents is an essential need to… read more here.
Keywords: scorpion venom; new cationic; iranian scorpion; scorpion ... See more keywords
Therapeutic Potential of Bee and Scorpion Venom Phospholipase A2 (PLA2): A Narrative Review
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DOI: 10.30476/ijms.2021.88511.1927
Abstract: Venomous arthropods such as scorpions and bees form one of the important groups with an essential role in medical entomology. Their venom possesses a mixture of diverse compounds, such as peptides, some of which have… read more here.
Keywords: pla2; venom; phospholipase pla2; bee scorpion ... See more keywords
The inhibitory potential of three scorpion venom peptides against multidrug-resistant Klebsiella pnemoniae
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DOI: 10.3389/fmicb.2025.1569719
Abstract: Background The rise of drug-resistant bacterial infections, particularly those caused by Klebsiella pneumoniae underscores the urgent need for novel therapeutic candidates. Hospital-acquired infections from K. pneumoniae carbapenemase (KPC)-producing bacteria pose a serious health threat, particularly… read more here.
Keywords: scorpion venom; potential three; multidrug resistant; inhibitory potential ... See more keywords