Abstract 1724: SCR-8388, a potent and selective SOS1::KRAS inhibitor, is effective in KRAS-addicted cancers
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DOI: 10.1158/1538-7445.am2023-1724
Abstract: KRAS occurs Mutation in approximately one in seven of all human cancers, making it the most frequently mutated oncogene. The activation of KRAS protein is regulated via switching the cycle between the active form, guanosine-… read more here.
Keywords: cell; sos1; kras mutant; scr 8388 ... See more keywords