Tac1-Expressing Neurons in the Periaqueductal Gray Facilitate the Itch-Scratching Cycle via Descending Regulation
Sign Up to like & getrecommendations! Published in 2019 at "Neuron"
DOI: 10.1016/j.neuron.2018.11.010
Abstract: Uncontrollable itch-scratching cycles lead to serious skin damage in patients with chronic itch. However, the neural mechanism promoting the itch-scratching cycle remains elusive. Here, we report that tachykinin 1 (Tac1)-expressing glutamatergic neurons in the lateral… read more here.
Keywords: itch scratching; itch; scratching behavior; scratching cycle ... See more keywords
Comparative Study on Different Skin Pruritus Mouse Models
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.630237
Abstract: The animal model is an important tool to study the mechanism of disease formation. Different animal models of pruritus have been adopted based on the purpose of researchers in the study of the itching mechanism.… read more here.
Keywords: scratching behavior; animal model; pruritus; study ... See more keywords
Reducing scratching behavior in atopic dermatitis patients using the EMDR treatment protocol for urge: A pilot study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2023.1101935
Abstract: Background Itch, and thereby the scratching behavior, is a common complaint in atopic dermatitis. Scratching damages the skin, which in turn worsens the itch. This itch-scratch cycle perpetuates the skin condition and has a major… read more here.
Keywords: emdr treatment; scratching behavior; treatment protocol; atopic dermatitis ... See more keywords
Oxytocin Elicits Itch Scratching Behavior via Spinal GRP/GRPR System
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2020.581977
Abstract: Oxytocin (OT), a neuropeptide involved in the regulation of complex social and sexual behavior in mammals, has been proposed as a treatment for a number of psychiatric disorders including pain. It has been well documented… read more here.
Keywords: spinal grp; itch scratching; grp grpr; scratching behavior ... See more keywords