Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli
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DOI: 10.1038/s42003-021-02490-7
Abstract: Most single point mutations destabilize folded proteins. Mutations that stabilize a protein typically only have a small effect and multiple mutations are often needed to substantially increase the stability. Multiple point mutations may act synergistically… read more here.
Keywords: synergistic stabilization; screen coli; stability; chymotrypsin inhibitor ... See more keywords