A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia.
Sign Up to like & getrecommendations! Published in 2017 at "Cell stem cell"
DOI: 10.1016/j.stem.2017.01.011
Abstract: Efforts to identify pharmaceuticals to treat heritable metabolic liver diseases have been hampered by the lack of models. However, cells with hepatocyte characteristics can be produced from induced pluripotent stem cells (iPSCs). Here, we have used hepatocyte-like… read more here.
Keywords: screen using; hepatocyte like; cardiac glycosides; like cells ... See more keywords
Rapid drug screen using 3D tumor organoids
Sign Up to like & getrecommendations! Published in 2018 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aar7507
Abstract: Breast cancer organoids enable high-throughput functional drug screens to potentially guide individualized therapy. Breast cancer organoids enable high-throughput functional drug screens to potentially guide individualized therapy. read more here.
Keywords: screen using; rapid drug; tumor organoids; drug ... See more keywords