Calculating maternal polygenic risk scores from prenatal screening by cell-free DNA data
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2025.1495604
Abstract: Polygenic Risk Scores (PRS) have enabled quantification of genetic risk for many common and complex traits. Here we developed a novel method to estimate maternal PRS using low-coverage whole genome sequencing data from prenatal screening… read more here.
Keywords: free dna; screening cell; prenatal screening; cell free ... See more keywords
Orthogonal Combinatorial Raman Codes Enable Rapid High-Throughput-Out Library Screening of Cell-Targeting Ligands
Sign Up to like & getrecommendations! Published in 2023 at "Research"
DOI: 10.34133/research.0136
Abstract: High-throughput assays play an important role in the fields of drug discovery, genetic analysis, and clinical diagnostics. Although super-capacity coding strategies may facilitate labeling and detecting large numbers of targets in a single assay, practically,… read more here.
Keywords: targeting ligands; screening cell; raman; high throughput ... See more keywords