Screening compound libraries for H2O2-mediated cancer therapeutics using a peroxiredoxin-based sensor.
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DOI: 10.1016/j.chembiol.2021.09.003
Abstract: Compounds that modulate H2O2 reaction networks have applications as targeted cancer therapeutics, as a subset of cancers exhibit sensitivity to this redox signal. Previous studies to identify therapeutics that induce oxidants have relied upon probes… read more here.
Keywords: peroxiredoxin; h2o2 mediated; screening compound; cancer therapeutics ... See more keywords