Structure-Based Screening of DNA GyraseB Inhibitors for Therapeutic Applications in Tuberculosis: a Pharmacoinformatics Study
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DOI: 10.1007/s12010-020-03374-y
Abstract: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (MTB) and considered as serious public health concern worldwide which kills approximately five thousand people every day. Therefore, TB drug development efforts are in gigantic… read more here.
Keywords: drug; structure based; tuberculosis; screening dna ... See more keywords
In Silico Screening of DNA Gyrase B Potent Flavonoids for the Treatment of Clostridium difficile Infection from PhytoHub Database
Sign Up to like & getrecommendations! Published in 2021 at "Brazilian Archives of Biology and Technology"
DOI: 10.1590/1678-4324-2021200402
Abstract: HIGHLIGHTS Flavonoids potentially target GyrB. Screened flavonoids have good bioavailability and no toxicity. Flavonoids could preferentially interact with GyrB and some of them exhibit higher binding affinity towards GyrB than novobiocin. read more here.
Keywords: dna gyrase; potent flavonoids; gyrase potent; screening dna ... See more keywords