An Analysis of Different Components of a High-Throughput Screening Library
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DOI: 10.1021/acs.jcim.8b00258
Abstract: Since many projects at pharmaceutical organizations get their start from a high-throughput screening (HTS) campaign, improving the quality of the HTS deck can improve the likelihood of discovering a high-quality lead molecule that can be… read more here.
Keywords: screening library; hit rates; high throughput; analysis different ... See more keywords
Screening of a Library of Oligosaccharides Targeting Lectin LecB of Pseudomonas Aeruginosa and Synthesis of High Affinity Oligoglycoclusters
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DOI: 10.3390/molecules23123073
Abstract: The Gram negative bacterium Pseudomonas aeruginosa (PA) is an opportunistic bacterium that causes severe and chronic infection of immune-depressed patients. It has the ability to form a biofilm that gives a selective advantage to the… read more here.
Keywords: screening library; pseudomonas aeruginosa; affinity; lectin ... See more keywords
Virtual Screening of a Library of Naturally Occurring Anthraquinones for Potential Anti-Fouling Agents
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DOI: 10.3390/molecules28030995
Abstract: Marine biofouling is the undesired accumulation of organic molecules, microorganisms, macroalgae, marine invertebrates, and their by-products on submerged surfaces. It is a serious challenge for marine vessels and the oil, gas, and renewable energy industries,… read more here.
Keywords: library naturally; fouling agents; virtual screening; anti fouling ... See more keywords