Chemical profiling and antioxidants screening from natural products: using CiNingJi as an example
Sign Up to like & getrecommendations! Published in 2022 at "Food Science and Biotechnology"
DOI: 10.1007/s10068-022-01049-4
Abstract: Natural products with good antioxidative properties have been paid increased attention globally. However, due to its chemical complexity, it is difficult to find out its antioxidative compounds. Herein, the chemical profiling and antioxidant capacity of… read more here.
Keywords: screening natural; antioxidants screening; natural products; example ... See more keywords
In Silico Screening of Natural Products as Potential Inhibitors of SARS-CoV-2 Using Molecular Docking Simulation
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-021-3504-5
Abstract: To explore potential natural products against severe acute respiratory syndrome coronavirus (SARS-CoV-2) via the study of structural and non-structural proteins of human coronaviruses. In this study, we performed an in-silico survey of 25 potential natural… read more here.
Keywords: silico screening; sars cov; screening natural; molecular docking ... See more keywords
Discovery of Aldehyde Dehydrogenase as a Potential Fungicide Target and Screening of its Natural Inhibitors against Fusarium verticillioides.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c05553
Abstract: Fusarium verticillioides is the primary pathogen causing ear rot and stalk rot in corn (Zea mays). It not only affects yields but also produces mycotoxins endangering both human and animal health. Aldehyde dehydrogenase (ALDH) is… read more here.
Keywords: aldehyde dehydrogenase; discovery aldehyde; target; screening natural ... See more keywords
An endoplasmic reticulum-targeting hydroxyl radical fluorescent probe for imaging of ferroptosis and screening of natural protectants
Sign Up to like & getrecommendations! Published in 2025 at "Chemical Science"
DOI: 10.1039/d4sc07953a
Abstract: The real-time and in situ detection of hydroxyl radicals (˙OH) in the endoplasmic reticulum (ER) is helpful to understand ferroptosis at its very early stage due to the crucial role of ˙OH in the ER… read more here.
Keywords: natural protectants; endoplasmic reticulum; fluorescent probe; ferroptosis ... See more keywords
Screening natural inhibitors against upregulated G-protein coupled receptors as potential therapeutics of Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1817784
Abstract: Abstract Computational approaches have been helpful in high throughput screening of drug libraries and designing ligands against receptors. Alzheimer's disease is a complex neurological disorder, which causes dementia. In this disease neurons are damaged due… read more here.
Keywords: inhibitors upregulated; upregulated protein; screening natural; natural inhibitors ... See more keywords
Screening of natural phenazine producers for electroactivity in bioelectrochemical systems
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.14199
Abstract: Mediated extracellular electron transfer (EET) might be a great vehicle to connect microbial bioprocesses with electrochemical control in stirred‐tank bioreactors. However, mediated electron transfer to date is not only much less efficient but also much… read more here.
Keywords: bioelectrochemical systems; electron transfer; phenazine; natural phenazine ... See more keywords
Phytochemical and Pharmacological Screening of Natural Oils to Study Their Synergistic Activity with Aceclofenac
Sign Up to like & getrecommendations! Published in 2024 at "Indian Journal of Animal Research"
DOI: 10.18805/ijar.b-5459
Abstract: Background: Drug aceclofenac is commonly used as an analgesics both topically and orally. Though it has diverse side effects related to oral delivery. Aim of recent work is to design and optimize a transdermal gel… read more here.
Keywords: activity aceclofenac; pharmacological screening; natural oils; phytochemical pharmacological ... See more keywords
Computational Screening of the Natural Product Osthole and Its Derivates for Anti-Inflammatory Activity
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12040505
Abstract: Osthole (OS) is a natural coumarin with a long history of medicinal use in a variety of diseases, such as itch and menstrual disorders. In recent years, OS has been shown to treat inflammation and… read more here.
Keywords: product osthole; osthole; computational screening; activity ... See more keywords
Computational Screening of Natural Compounds for Identification of Potential Anti-Cancer Agents Targeting MCM7 Protein
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26195878
Abstract: Minichromosome maintenance complex component 7 (MCM7) is involved in replicative licensing and the synthesis of DNA, and its overexpression is a fascinating biomarker for various cancer types. There is currently no effective agent that can… read more here.
Keywords: screening natural; computational screening; cancer; mcm7 protein ... See more keywords
Screening of Natural Products Inhibitors of SARS-CoV-2 Entry
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27051743
Abstract: The COVID-19 pandemic has led to the search for new molecules with antiviral activity against SARS-CoV-2. The entry of the virus into the cell is one of the main targets for inhibiting SARS-CoV-2 infection. Natural… read more here.
Keywords: sars cov; entry; cov entry; products inhibitors ... See more keywords