Screening of potential microbial markers for lung cancer using metagenomic sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5513
Abstract: Lung cancer is the most prevalent cancer with high mortality in China, and it is associated with the dysbiosis of the lung microbiome. This study attempted to screen for specific microorganisms as potential biomarkers for… read more here.
Keywords: lung cancer; microbial markers; screening potential; potential microbial ... See more keywords
Screening of potential novel candidate genes in schwannomatosis patients
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24424
Abstract: Schwannomatosis comprises a group of hereditary tumor predisposition syndromes characterized by, usually benign, multiple nerve sheath tumors, which frequently cause severe pain that does not typically respond to drug treatments. The most common schwannomatosisâassociated gene… read more here.
Keywords: genes schwannomatosis; candidate genes; screening potential; schwannomatosis patients ... See more keywords
The antioxidant screening of potential materials for drugs based on 6-nitro-1,2,4-triazoloazines containing natural polyphenol fragments
Sign Up to like & getrecommendations! Published in 2020 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-02466-2
Abstract: The course of viral diseases is accompanied by excessive generation of active oxygen metabolites, so the effectiveness of treatment can be improved by combining antiviral and antioxidant therapy. There was a screening of antioxidant properties… read more here.
Keywords: materials drugs; antioxidant capacity; antioxidant screening; screening potential ... See more keywords
Screening of potential endoglucanases, hydrolysis conditions and different sugarcane straws pretreatments for cello-oligosaccharides production.
Sign Up to like & getrecommendations! Published in 2020 at "Bioresource technology"
DOI: 10.1016/j.biortech.2020.123918
Abstract: Cello-oligosaccharides (COS) are oligomers with 2 to 6 β-1,4-linked glucose units, with potential applications in the food/feed and bioenergy industrial sectors. In this study, the combination of five heterologous expressed endoglucanases varying the temperature and… read more here.
Keywords: cello oligosaccharides; sugarcane straws; screening potential; production ... See more keywords
Screening of Potential PFOS Alternatives To Decrease Liver Bioaccumulation: Experimental and Computational Approaches.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental science & technology"
DOI: 10.1021/acs.est.8b05564
Abstract: Perfluorooctanesulfonate (PFOS) is a persistent organic pollutant with significant bioaccumulation potential in liver tissues. Exposure to PFOS could cause increase of liver weight, induce adenomas of the liver, and cause hepatomegaly. Alternatives of PFOS might… read more here.
Keywords: pfos alternatives; screening potential; pfos; liver bioaccumulation ... See more keywords
Screening of potential hub genes and key pathways associated with breast cancer by bioinformatics tools
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033291
Abstract: Breast cancer (BC) remains the leading cause of cancer-related death in women worldwide. The development of new targeted therapies that may improve patient survival remains an area of growing interest. This study aimed to identify… read more here.
Keywords: screening potential; hub genes; breast cancer; cancer ... See more keywords
Efficient Data Mining Algorithms for Screening Potential Proteins of Drug Target
Sign Up to like & getrecommendations! Published in 2017 at "Mathematical Problems in Engineering"
DOI: 10.1155/2017/9852063
Abstract: The past few decades have witnessed the boom in pharmacology as well as the dilemma of drug development. Playing a crucial role in drug design, the screening of potential human proteins of drug targets from… read more here.
Keywords: dtps; screening potential; drug; drug target ... See more keywords
Computational screening for potential drug candidates against the SARS-CoV-2 main protease.
Sign Up to like & getrecommendations! Published in 2020 at "F1000Research"
DOI: 10.12688/f1000research.23829.1
Abstract: Background: SARS-CoV-2 is the causal agent of the current coronavirus disease 2019 (COVID-19) pandemic. They are enveloped, positive-sense, single-stranded RNA viruses of the Coronaviridae family. Proteases of SARS-CoV-2 are necessary for viral replication, structural assembly,… read more here.
Keywords: protease; screening potential; computational screening; potential drug ... See more keywords
High-Throughput Screening for the Potential Inhibitors of SARS-CoV-2 with Essential Dynamic Behavior.
Sign Up to like & getrecommendations! Published in 2023 at "Current drug targets"
DOI: 10.2174/1389450124666230306141725
Abstract: Global health security has been challenged by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic. Due to the lengthy process of generating vaccinations, it is vital to reposition currently available drugs in order to… read more here.
Keywords: potential inhibitors; screening potential; throughput screening; high throughput ... See more keywords
In Vitro and In Vivo Approaches for Screening the Potential of Anti Cancer Agents: A Review.
Sign Up to like & getrecommendations! Published in 2022 at "Current drug discovery technologies"
DOI: 10.2174/1570163819666220106122811
Abstract: BACKGROUND Anticancer drug development is a tedious process, requiring several in vitro, in vivo, and clinical studies. To avoid chemical toxicity in animals during an experiment, it is necessary to envisage toxic doses of screened… read more here.
Keywords: cell based; vitro vivo; approaches screening; screening potential ... See more keywords
Screening of Potential Vibrio cholerae Bacteriophages for Cholera Therapy: A Comparative Genomic Approach
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.803933
Abstract: Cholera continues to be a major burden for developing nations, especially where sanitation, quality of water supply, and hospitalization have remained an issue. Recently, growing antimicrobial-resistant strains of Vibrio cholerae underscores alternative therapeutic strategies for… read more here.
Keywords: approach; screening potential; vibrio cholerae; therapy ... See more keywords